Structural mechanism of SARS-CoV-2 neutralization by two murine antibodies targeting the RBD

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has necessitated the rapid development of antibody-based therapies and vaccines as countermeasures. Here, we use cryoelectron microscopy (cryo-EM) to characterize two protective anti-SARS-CoV-2 murine monoclonal antibodies (mA...

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Detalles Bibliográficos
Autores principales: Errico, John M., Zhao, Haiyan, Chen, Rita E., Liu, Zhuoming, Case, James Brett, Ma, Meisheng, Schmitz, Aaron J., Rau, Michael J., Fitzpatrick, James A.J., Shi, Pei-Yong, Diamond, Michael S., Whelan, Sean P.J., Ellebedy, Ali H., Fremont, Daved H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8498651/
https://www.ncbi.nlm.nih.gov/pubmed/34655519
http://dx.doi.org/10.1016/j.celrep.2021.109881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8498651/
https://www.ncbi.nlm.nih.gov/pubmed/34655519
http://dx.doi.org/10.1016/j.celrep.2021.109881

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