Anti-glomerular basement membrane disease with intense nephrotic syndrome: a new case report

Anti-glomerular basement membrane (anti-GBM) disease was usually described as a small vessel vasculitis presenting with acute kidney injury, haematuria and non-nephrotic proteinuria. We report a case of anti-GBM disease revealed by an intense nephrotic syndrome. The urinary protein level was 12g/day...

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Autores principales: Mami, Ikram, Ghzel, Emna, Abida, Rym, Hlaoui, Fadwa, Jebali, Hela, Rais, Lamia, Beji, Soumaya, Hamida, Fethi Ben, Fatma, Lilia Ben, Zouaghi, Karim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8498661/
https://www.ncbi.nlm.nih.gov/pubmed/34659616
http://dx.doi.org/10.11604/pamj.2021.39.243.30461
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author Mami, Ikram
Ghzel, Emna
Abida, Rym
Hlaoui, Fadwa
Jebali, Hela
Rais, Lamia
Beji, Soumaya
Hamida, Fethi Ben
Fatma, Lilia Ben
Zouaghi, Karim
author_facet Mami, Ikram
Ghzel, Emna
Abida, Rym
Hlaoui, Fadwa
Jebali, Hela
Rais, Lamia
Beji, Soumaya
Hamida, Fethi Ben
Fatma, Lilia Ben
Zouaghi, Karim
author_sort Mami, Ikram
collection PubMed
description Anti-glomerular basement membrane (anti-GBM) disease was usually described as a small vessel vasculitis presenting with acute kidney injury, haematuria and non-nephrotic proteinuria. We report a case of anti-GBM disease revealed by an intense nephrotic syndrome. The urinary protein level was 12g/day. Renal biopsy only showed crescent glomerulonephritis with linear staining of IgG in direct immunofluorescence without other glomerulonephritis. Immunoglobulin G (IgG) anti-GBM antibody titer was elevated.
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spelling pubmed-84986612021-10-15 Anti-glomerular basement membrane disease with intense nephrotic syndrome: a new case report Mami, Ikram Ghzel, Emna Abida, Rym Hlaoui, Fadwa Jebali, Hela Rais, Lamia Beji, Soumaya Hamida, Fethi Ben Fatma, Lilia Ben Zouaghi, Karim Pan Afr Med J Case Report Anti-glomerular basement membrane (anti-GBM) disease was usually described as a small vessel vasculitis presenting with acute kidney injury, haematuria and non-nephrotic proteinuria. We report a case of anti-GBM disease revealed by an intense nephrotic syndrome. The urinary protein level was 12g/day. Renal biopsy only showed crescent glomerulonephritis with linear staining of IgG in direct immunofluorescence without other glomerulonephritis. Immunoglobulin G (IgG) anti-GBM antibody titer was elevated. The African Field Epidemiology Network 2021-08-16 /pmc/articles/PMC8498661/ /pubmed/34659616 http://dx.doi.org/10.11604/pamj.2021.39.243.30461 Text en Copyright: Ikram Mami et al. https://creativecommons.org/licenses/by/4.0/The Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Mami, Ikram
Ghzel, Emna
Abida, Rym
Hlaoui, Fadwa
Jebali, Hela
Rais, Lamia
Beji, Soumaya
Hamida, Fethi Ben
Fatma, Lilia Ben
Zouaghi, Karim
Anti-glomerular basement membrane disease with intense nephrotic syndrome: a new case report
title Anti-glomerular basement membrane disease with intense nephrotic syndrome: a new case report
title_full Anti-glomerular basement membrane disease with intense nephrotic syndrome: a new case report
title_fullStr Anti-glomerular basement membrane disease with intense nephrotic syndrome: a new case report
title_full_unstemmed Anti-glomerular basement membrane disease with intense nephrotic syndrome: a new case report
title_short Anti-glomerular basement membrane disease with intense nephrotic syndrome: a new case report
title_sort anti-glomerular basement membrane disease with intense nephrotic syndrome: a new case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8498661/
https://www.ncbi.nlm.nih.gov/pubmed/34659616
http://dx.doi.org/10.11604/pamj.2021.39.243.30461
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