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Effect of mydriasis with topical rocuronium bromide on electroretinography in domestic pigeons (Columba livia)

This study aimed to investigate the effect of mydriasis using topical rocuronium bromide on electroretinography (ERG) in domestic pigeons (Columba livia). Scotopic mixed rod and cone, photopic cone, and photopic flicker ERG were performed on nine eyes of nine healthy adult pigeons under sedation. Ea...

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Autores principales: SUSANTI, Lina, KANG, Seonmi, KIM, Sunhyo, PARK, Sanghyun, LEE, Songhui, KIM, Su An, SEO, Kangmoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8498831/
https://www.ncbi.nlm.nih.gov/pubmed/34261835
http://dx.doi.org/10.1292/jvms.21-0224
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author SUSANTI, Lina
KANG, Seonmi
KIM, Sunhyo
PARK, Sanghyun
LEE, Songhui
KIM, Su An
SEO, Kangmoon
author_facet SUSANTI, Lina
KANG, Seonmi
KIM, Sunhyo
PARK, Sanghyun
LEE, Songhui
KIM, Su An
SEO, Kangmoon
author_sort SUSANTI, Lina
collection PubMed
description This study aimed to investigate the effect of mydriasis using topical rocuronium bromide on electroretinography (ERG) in domestic pigeons (Columba livia). Scotopic mixed rod and cone, photopic cone, and photopic flicker ERG were performed on nine eyes of nine healthy adult pigeons under sedation. Each pigeon underwent two sets of ERG recordings. First, without the induction of mydriasis (control) and the second time with the induction of mydriasis using topical rocuronium bromide (treatment). The results were compared using either the Student’s t-test or Wilcoxon rank-sum test, where a P-value of <0.05 was considered statistically significant. No significant differences were observed in the a- and b-wave implicit times and amplitudes during scotopic ERG between the two groups. The a- and b-wave amplitudes in the photopic cone were significantly higher in the treatment group (63.83 ± 32.33 and 191.75 ± 94.46 µV) compared to the control group (46.15 ± 27.60 and 116.76 ± 70.65 µV; P=0.045 and P=0.032, respectively). The photopic flicker amplitude was also significantly higher in the treatment group (76.23 ± 48.56 µV) than in the control group (42.18 ± 31.18 µV; P=0.044). No statistically significant differences were observed in the photopic cone and flicker implicit times between both groups. In conclusions, mydriasis induced by rocuronium bromide in pigeon resulting in higher amplitudes during the photopic ERG but not scotopic ERG.
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spelling pubmed-84988312021-10-13 Effect of mydriasis with topical rocuronium bromide on electroretinography in domestic pigeons (Columba livia) SUSANTI, Lina KANG, Seonmi KIM, Sunhyo PARK, Sanghyun LEE, Songhui KIM, Su An SEO, Kangmoon J Vet Med Sci Wildlife Science This study aimed to investigate the effect of mydriasis using topical rocuronium bromide on electroretinography (ERG) in domestic pigeons (Columba livia). Scotopic mixed rod and cone, photopic cone, and photopic flicker ERG were performed on nine eyes of nine healthy adult pigeons under sedation. Each pigeon underwent two sets of ERG recordings. First, without the induction of mydriasis (control) and the second time with the induction of mydriasis using topical rocuronium bromide (treatment). The results were compared using either the Student’s t-test or Wilcoxon rank-sum test, where a P-value of <0.05 was considered statistically significant. No significant differences were observed in the a- and b-wave implicit times and amplitudes during scotopic ERG between the two groups. The a- and b-wave amplitudes in the photopic cone were significantly higher in the treatment group (63.83 ± 32.33 and 191.75 ± 94.46 µV) compared to the control group (46.15 ± 27.60 and 116.76 ± 70.65 µV; P=0.045 and P=0.032, respectively). The photopic flicker amplitude was also significantly higher in the treatment group (76.23 ± 48.56 µV) than in the control group (42.18 ± 31.18 µV; P=0.044). No statistically significant differences were observed in the photopic cone and flicker implicit times between both groups. In conclusions, mydriasis induced by rocuronium bromide in pigeon resulting in higher amplitudes during the photopic ERG but not scotopic ERG. The Japanese Society of Veterinary Science 2021-07-13 2021-09 /pmc/articles/PMC8498831/ /pubmed/34261835 http://dx.doi.org/10.1292/jvms.21-0224 Text en ©2021 The Japanese Society of Veterinary Science https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Wildlife Science
SUSANTI, Lina
KANG, Seonmi
KIM, Sunhyo
PARK, Sanghyun
LEE, Songhui
KIM, Su An
SEO, Kangmoon
Effect of mydriasis with topical rocuronium bromide on electroretinography in domestic pigeons (Columba livia)
title Effect of mydriasis with topical rocuronium bromide on electroretinography in domestic pigeons (Columba livia)
title_full Effect of mydriasis with topical rocuronium bromide on electroretinography in domestic pigeons (Columba livia)
title_fullStr Effect of mydriasis with topical rocuronium bromide on electroretinography in domestic pigeons (Columba livia)
title_full_unstemmed Effect of mydriasis with topical rocuronium bromide on electroretinography in domestic pigeons (Columba livia)
title_short Effect of mydriasis with topical rocuronium bromide on electroretinography in domestic pigeons (Columba livia)
title_sort effect of mydriasis with topical rocuronium bromide on electroretinography in domestic pigeons (columba livia)
topic Wildlife Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8498831/
https://www.ncbi.nlm.nih.gov/pubmed/34261835
http://dx.doi.org/10.1292/jvms.21-0224
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