CHAF1A Blocks Neuronal Differentiation and Promotes Neuroblastoma Oncogenesis via Metabolic Reprogramming

Neuroblastoma (NB) arises from oncogenic disruption of neural crest (NC) differentiation. Treatment with retinoic acid (RA) to induce differentiation has improved survival in some NB patients, but not all patients respond, and most NBs eventually develop resistance to RA. Loss of the chromatin modif...

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Detalles Bibliográficos
Autores principales: Tao, Ling, Moreno‐Smith, Myrthala, Ibarra‐García‐Padilla, Rodrigo, Milazzo, Giorgio, Drolet, Nathan A., Hernandez, Blanca E., Oh, Young S., Patel, Ivanshi, Kim, Jean J., Zorman, Barry, Patel, Tajhal, Kamal, Abu Hena Mostafa, Zhao, Yanling, Hicks, John, Vasudevan, Sanjeev A., Putluri, Nagireddy, Coarfa, Cristian, Sumazin, Pavel, Perini, Giovanni, Parchem, Ronald J., Uribe, Rosa A., Barbieri, Eveline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8498874/
https://www.ncbi.nlm.nih.gov/pubmed/34365742
http://dx.doi.org/10.1002/advs.202005047

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