Cargando…
Combined Therapy With Avastin, a PAF Receptor Antagonist and a Lipid Mediator Inhibited Glioblastoma Tumor Growth
Glioblastoma multiforme (GBM) is an aggressive, highly proliferative, invasive brain tumor with a poor prognosis and low survival rate. The current standard of care for GBM is chemotherapy combined with radiation following surgical intervention, altogether with limited efficacy, since survival avera...
Autores principales: | Cruz Flores, Valerie A., Menghani, Hemant, Mukherjee, Pranab K., Marrero, Luis, Obenaus, Andre, Dang, Quan, Khoutorova, Larissa, Reid, Madigan M., Belayev, Ludmila, Bazan, Nicolas G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8498947/ https://www.ncbi.nlm.nih.gov/pubmed/34630114 http://dx.doi.org/10.3389/fphar.2021.746470 |
Ejemplares similares
-
Synergistic Neuroprotection by a PAF Antagonist Plus a Docosanoid in Experimental Ischemic Stroke: Dose-Response and Therapeutic Window
por: Reid, Madigan M., et al.
Publicado: (2022) -
DHA modulates MANF and TREM2 abundance, enhances neurogenesis, reduces infarct size, and improves neurological function after experimental ischemic stroke
por: Belayev, Ludmila, et al.
Publicado: (2020) -
Integrated inflammatory signaling landscape response after delivering Elovanoid free-fatty-acid precursors leading to experimental stroke neuroprotection
por: Reid, Madigan M., et al.
Publicado: (2023) -
Neuroprotectin D1 upregulates Iduna expression and provides protection in cellular uncompensated oxidative stress and in experimental ischemic stroke
por: Belayev, Ludmila, et al.
Publicado: (2017) -
Elovanoids are a novel class of homeostatic lipid mediators that protect neural cell integrity upon injury
por: Bhattacharjee, Surjyadipta, et al.
Publicado: (2017)