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Enantioenriched α-Vinyl 1,4-Benzodiazepines and 1,4-Benzoxazepines via Enantioselective Rhodium-Catalyzed Hydrofunctionalizations of Alkynes and Allenes

[Image: see text] Benzofused seven-membered heterocycles such as 1,4-benzo[e]diazepines (1,4-BZDs) and 1,4-benzo[e]oxazepines (1,4-BZOs) were efficiently synthesized by Rh-catalyzed hydrofunctionalization of internal alkynes and allenes in good to excellent yields. The asymmetric hydroamination of (...

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Detalles Bibliográficos
Autores principales: Velasco-Rubio, Álvaro, Bernárdez, Rodrigo, Varela, Jesús A., Saá, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8499028/
https://www.ncbi.nlm.nih.gov/pubmed/34259003
http://dx.doi.org/10.1021/acs.joc.1c01268

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