Detection by fluorescence of pituitary neuroendocrine tumour (PitNET) tissue during endoscopic transsphenoidal surgery using bevacizumab-800CW (DEPARTURE trial): study protocol for a non-randomised, non-blinded, single centre, feasibility and dose-finding trial

INTRODUCTION: Achieving gross total resection and endocrine remission in pituitary neuroendocrine tumours (PitNET) can be challenging, especially in PitNETs with cavernous sinus (CS) invasion, defined as a Knosp grade of 3 or 4. A potential target to identify PitNET tissue is vascular endothelial gr...

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Detalles Bibliográficos
Autores principales: Vergeer, Rob A, Postma, Mark R, Schmidt, Iris, Korsten-Meijer, Astrid GW, Feijen, Robert A, Kruijff, Schelto, Nagengast, Wouter B, van Dijk, J Marc C, den Dunnen, Wilfred F A, van Beek, André P, Kuijlen, Jos M A, van den Berg, Gerrit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Diabetes and Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8499267/
https://www.ncbi.nlm.nih.gov/pubmed/34620658
http://dx.doi.org/10.1136/bmjopen-2021-049109

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