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Alloantigen-activated (AAA) CD4(+) T cells reinvigorate host endogenous T cell immunity to eliminate pre-established tumors in mice
BACKGROUND: Cancer vaccines that induce endogenous antitumor immunity represent an ideal strategy to overcome intractable cancers. However, doing this against a pre-established cancer using autologous immune cells has proven to be challenging. “Allogeneic effects” refers to the induction of an endog...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8499505/ https://www.ncbi.nlm.nih.gov/pubmed/34625113 http://dx.doi.org/10.1186/s13046-021-02102-6 |