Alloantigen-activated (AAA) CD4(+) T cells reinvigorate host endogenous T cell immunity to eliminate pre-established tumors in mice

BACKGROUND: Cancer vaccines that induce endogenous antitumor immunity represent an ideal strategy to overcome intractable cancers. However, doing this against a pre-established cancer using autologous immune cells has proven to be challenging. “Allogeneic effects” refers to the induction of an endog...

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Detalles Bibliográficos
Autores principales: Mochizuki, Kazuhiro, Kobayashi, Shogo, Takahashi, Nobuhisa, Sugimoto, Kotaro, Sano, Hideki, Ohara, Yoshihiro, Mineishi, Shin, Zhang, Yi, Kikuta, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8499505/
https://www.ncbi.nlm.nih.gov/pubmed/34625113
http://dx.doi.org/10.1186/s13046-021-02102-6

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