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Comutations in DDR Pathways Predict Atezolizumab Response in Non-Small Cell Lung Cancer Patients
The presence of comutations (co-mut+) in DNA damage response and repair (DDR) pathways was associated with improved survival for immune checkpoint inhibitor (ICI) therapy in non-small cell lung cancer (NSCLC). However, it remains unknown whether co-mut+ status could be a predictive biomarker for imm...
Autores principales: | Xiong, Anning, Nie, Wei, Zhou, Yan, Li, Changhui, Gu, Kai, Zhang, Ding, Chen, Shiqing, Wen, Fengcai, Zhong, Hua, Han, Baohui, Zhang, Xueyan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8499805/ https://www.ncbi.nlm.nih.gov/pubmed/34630387 http://dx.doi.org/10.3389/fimmu.2021.708558 |
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