A genetic link between risk for Alzheimer's disease and severe COVID-19 outcomes via the OAS1 gene

Recently, we reported oligoadenylate synthetase 1 (OAS1) contributed to the risk of Alzheimer’s disease, by its enrichment in transcriptional networks expressed by microglia. However, the function of OAS1 within microglia was not known. Using genotyping from 1313 individuals with sporadic Alzheimer’...

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Detalles Bibliográficos
Autores principales: Magusali, Naciye, Graham, Andrew C, Piers, Thomas M, Panichnantakul, Pantila, Yaman, Umran, Shoai, Maryam, Reynolds, Regina H, Botia, Juan A, Brookes, Keeley J, Guetta-Baranes, Tamar, Bellou, Eftychia, Bayram, Sevinc, Sokolova, Dimitra, Ryten, Mina, Sala Frigerio, Carlo, Escott-Price, Valentina, Morgan, Kevin, Pocock, Jennifer M, Hardy, John, Salih, Dervis A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500089/
https://www.ncbi.nlm.nih.gov/pubmed/34619763
http://dx.doi.org/10.1093/brain/awab337

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