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A novel AST2 mutation generated upon whole-genome transformation of Saccharomyces cerevisiae confers high tolerance to 5-Hydroxymethylfurfural (HMF) and other inhibitors

Development of cell factories for conversion of lignocellulosic biomass hydrolysates into biofuels or bio-based chemicals faces major challenges, including the presence of inhibitory chemicals derived from biomass hydrolysis or pretreatment. Extensive screening of 2526 Saccharomyces cerevisiae strai...

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Detalles Bibliográficos
Autores principales:	Vanmarcke, Gert, Deparis, Quinten, Vanthienen, Ward, Peetermans, Arne, Foulquié-Moreno, Maria R., Thevelein, Johan M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500407/ https://www.ncbi.nlm.nih.gov/pubmed/34624020 http://dx.doi.org/10.1371/journal.pgen.1009826

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