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Loss of telomere silencing is accompanied by dysfunction of Polo kinase and centrosomes during Drosophila oogenesis and early development

Telomeres are nucleoprotein complexes that protect the ends of eukaryotic linear chromosomes from degradation and fusions. Telomere dysfunction leads to cell growth arrest, oncogenesis, and premature aging. Telomeric RNAs have been found in all studied species; however, their functions and biogenesi...

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Detalles Bibliográficos
Autores principales: Morgunova, Valeriya, Kordyukova, Maria, Mikhaleva, Elena A., Butenko, Ivan, Pobeguts, Olga V., Kalmykova, Alla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500440/
https://www.ncbi.nlm.nih.gov/pubmed/34624021
http://dx.doi.org/10.1371/journal.pone.0258156