Cargando…

Metabolic responsiveness to training depends on insulin sensitivity and protein content of exosomes in insulin-resistant males

High-intensity interval training (HIIT) improves cardiorespiratory fitness (VO(2)max), but its impact on metabolism remains unclear. We hypothesized that 12-week HIIT increases insulin sensitivity in males with or without type 2 diabetes [T2D and NDM (nondiabetic humans)]. However, despite identical...

Descripción completa

Detalles Bibliográficos
Autores principales:	Apostolopoulou, Maria, Mastrototaro, Lucia, Hartwig, Sonja, Pesta, Dominik, Straßburger, Klaus, de Filippo, Elisabetta, Jelenik, Tomas, Karusheva, Yanislava, Gancheva, Sofiya, Markgraf, Daniel, Herder, Christian, Nair, K. Sreekumaran, Reichert, Andreas S., Lehr, Stefan, Müssig, Karsten, Al-Hasani, Hadi, Szendroedi, Julia, Roden, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2021
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500512/ https://www.ncbi.nlm.nih.gov/pubmed/34623918 http://dx.doi.org/10.1126/sciadv.abi9551

Ejemplares similares

Short-term dietary reduction of branched-chain amino acids reduces meal-induced insulin secretion and modifies microbiome composition in type 2 diabetes: a randomized controlled crossover trial
por: Karusheva, Yanislava, et al.
Publicado: (2019)

Dynamic changes of muscle insulin sensitivity after metabolic surgery
por: Gancheva, Sofiya, et al.
Publicado: (2019)

Author Correction: Dynamic changes of muscle insulin sensitivity after metabolic surgery
por: Gancheva, Sofiya, et al.
Publicado: (2022)

Branched-Chain Amino Acids Associate Negatively With Postprandial Insulin Secretion in Recent-Onset Diabetes
por: Karusheva, Yanislava, et al.
Publicado: (2021)

NDUFB6 Polymorphism Is Associated With Physical Activity-Mediated Metabolic Changes in Type 2 Diabetes
por: Pesta, Dominik, et al.
Publicado: (2021)

Role of ceramide-to-dihydroceramide ratios for insulin resistance and non-alcoholic fatty liver disease in humans
por: Apostolopoulou, Maria, et al.
Publicado: (2020)

Reduced Muscle Strength Is Associated With Insulin Resistance in Type 2 Diabetes Patients With Osteoarthritis
por: Zaharia, Oana Patricia, et al.
Publicado: (2020)

Dietary palmitate and oleate differently modulate insulin sensitivity in human skeletal muscle
por: Sarabhai, Theresia, et al.
Publicado: (2021)

Habitual Fructose Intake Relates to Insulin Sensitivity and Fatty Liver Index in Recent-Onset Type 2 Diabetes Patients and Individuals without Diabetes
por: Weber, Katharina S., et al.
Publicado: (2018)

Expansion and Impaired Mitochondrial Efficiency of Deep Subcutaneous Adipose Tissue in Recent-Onset Type 2 Diabetes
por: Bódis, Kálmán, et al.
Publicado: (2019)

A New Targeted Lipidomics Approach Reveals Lipid Droplets in Liver, Muscle and Heart as a Repository for Diacylglycerol and Ceramide Species in Non-Alcoholic Fatty Liver
por: Preuss, Christina, et al.
Publicado: (2019)

Improving insulin sensitivity, liver steatosis and fibrosis in type 2 diabetes by a food-based digital education-assisted lifestyle intervention program: a feasibility study
por: Zaharia, Oana P., et al.
Publicado: (2021)

High-intensity interval training for 12 weeks improves cardiovascular autonomic function but not somatosensory nerve function and structure in overweight men with type 2 diabetes
por: Bönhof, Gidon J., et al.
Publicado: (2022)

Metabolic surgery-induced changes of the growth hormone system relate to improved adipose tissue function
por: Gancheva, Sofiya, et al.
Publicado: (2023)

An 8-week diet high in cereal fiber and coffee but free of red meat does not improve beta-cell function in patients with type 2 diabetes mellitus: a randomized controlled trial
por: Karusheva, Yanislava, et al.
Publicado: (2018)

Reduced expression of stearoyl-CoA desaturase-1, but not free fatty acid receptor 2 or 4 in subcutaneous adipose tissue of patients with newly diagnosed type 2 diabetes mellitus
por: Bódis, Kálmán, et al.
Publicado: (2018)

Cohort profile: the German Diabetes Study (GDS)
por: Szendroedi, Julia, et al.
Publicado: (2016)

Islet primary cilia motility controls insulin secretion
por: Cho, Jung Hoon, et al.
Publicado: (2022)

Reduced insulin signaling in neurons induces sex-specific health benefits
por: Baghdadi, Maarouf, et al.
Publicado: (2023)

Impact of mixed meal tolerance test composition on measures of beta-cell function in type 2 diabetes
por: Kössler, Theresa, et al.
Publicado: (2021)

Skeletal muscle NOX4 is required for adaptive responses that prevent insulin resistance
por: Xirouchaki, Chrysovalantou E., et al.
Publicado: (2021)

Mathematical model of insulin kinetics accounting for the amino acids effect during a mixed meal tolerance test
por: Morettini, Micaela, et al.
Publicado: (2022)

FGF21 regulates insulin sensitivity following long-term chronic stress
por: Jelenik, Tomas, et al.
Publicado: (2018)

Development of a physiological insulin resistance model in human stem cell–derived adipocytes
por: Friesen, Max, et al.
Publicado: (2022)

A common genetic variant of a mitochondrial RNA processing enzyme predisposes to insulin resistance
por: Rossetti, Giulia, et al.
Publicado: (2021)

Insulin Resistance and Vulnerability to Cardiac Ischemia
por: Jelenik, Tomas, et al.
Publicado: (2018)

Metabolic Factors Predict Changes in Endothelial Function During the Early Course of Type 1 and Type 2 Diabetes
por: Zaharia, Oana Patricia, et al.
Publicado: (2022)

Efficient oral insulin delivery enabled by transferrin-coated acid-resistant metal-organic framework nanoparticles
por: Zou, Jun-Jie, et al.
Publicado: (2022)

Starvation-induced changes in somatic insulin/IGF-1R signaling drive metabolic programming across generations
por: Vogt, Merly C., et al.
Publicado: (2023)

The adipocyte-enriched secretory protein tetranectin exacerbates type 2 diabetes by inhibiting insulin secretion from β cells
por: Liu, Fen, et al.
Publicado: (2022)

Mechanisms of Insulin Resistance in Primary and Secondary Nonalcoholic Fatty Liver
por: Jelenik, Tomas, et al.
Publicado: (2017)

A SOX2-engineered epigenetic silencer factor represses the glioblastoma genetic program and restrains tumor development
por: Benedetti, Valerio, et al.
Publicado: (2022)

TSC22D4 interacts with Akt1 to regulate glucose metabolism
por: Demir, Sevgican, et al.
Publicado: (2022)

Associations between cognitive performance and Mediterranean dietary pattern in patients with type 1 or type 2 diabetes mellitus
por: Kössler, Theresa, et al.
Publicado: (2020)

Association of a lifestyle score with cardiometabolic markers among individuals with diabetes: a cross-sectional study
por: Baechle, Christina, et al.
Publicado: (2023)

Associations between explorative dietary patterns and serum lipid levels and their interactions with ApoA5 and ApoE haplotype in patients with recently diagnosed type 2 diabetes
por: Weber, Katharina S., et al.
Publicado: (2016)

Lipidomics—Reshaping the Analysis and Perception of Type 2 Diabetes
por: Markgraf, Daniel F., et al.
Publicado: (2016)

Analyzing immune response to engineered hydrogels by hierarchical clustering of inflammatory cell subsets
por: Fernandez-Yague, Marc A., et al.
Publicado: (2022)

AKT/AMPK-mediated phosphorylation of TBC1D4 disrupts the interaction with insulin-regulated aminopeptidase
por: Eickelschulte, Samaneh, et al.
Publicado: (2021)

Brain insulin action on peripheral insulin sensitivity in women depends on menstrual cycle phase
por: Hummel, Julia, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_fosro3siqn7tlp2l12nrqtqjmu