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Tox2 is required for the maintenance of GC T(FH) cells and the generation of memory T(FH) cells

Memory T follicular helper (T(FH)) cells play an essential role to induce secondary antibody response by providing help to memory and naïve B cells. Here, we show that the transcription factor Tox2 is vital for the maintenance of T(FH) cells in germinal centers (GCs) and the generation of memory T(F...

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Detalles Bibliográficos
Autores principales: Horiuchi, Shu, Wu, Hanchih, Liu, Wen-Chun, Schmitt, Nathalie, Provot, Jonathan, Liu, Yang, Bentebibel, Salah-Eddine, Albrecht, Randy A., Schotsaert, Michael, Forst, Christian V., Zhang, Bin, Ueno, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500513/
https://www.ncbi.nlm.nih.gov/pubmed/34623911
http://dx.doi.org/10.1126/sciadv.abj1249