Primary Sclerosing Cholangitis–Associated Cholangiocarcinoma Demonstrates High Intertumor and Intratumor Heterogeneity

Intertumor and intratumor heterogeneity may explain the diagnostic challenge and limited efficacy of chemotherapy for primary sclerosing cholangitis–associated cholangiocarcinoma (PSC-CCA). In this study, tumor heterogeneity was assessed through p53 and p16 protein expression analysis and next-gener...

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Detalles Bibliográficos
Autores principales: Kamp, Eline J.C.A., Peppelenbosch, Maikel P., Doukas, Michail, Verheij, Joanne, Ponsioen, Cyriel Y., van Marion, Ronald, Bruno, Marco J., Koerkamp, Bas Groot, Dinjens, Winand N.M., de Vries, Annemarie C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500610/
https://www.ncbi.nlm.nih.gov/pubmed/34608877
http://dx.doi.org/10.14309/ctg.0000000000000410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500610/
https://www.ncbi.nlm.nih.gov/pubmed/34608877
http://dx.doi.org/10.14309/ctg.0000000000000410

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