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Is intraoperative corticosteroid a good choice for postoperative pain relief in total joint arthroplasty? A meta-analysis of 11 randomized controlled trials

BACKGROUND: Effective postoperative analgesia is of great significance for postoperative rehabilitation. This meta-analysis aimed to investigate the efficacy of corticosteroid on pain following total joint arthroplasty. METHOD: PubMed (1996–December 2020), Embase (1996–December 2020), and the Cochra...

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Autores principales: Zhang, Lu-kai, Zhu, Fang-bing, Gao, Huan-huan, Zhang, Lei, Quan, Ren-fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500626/
https://www.ncbi.nlm.nih.gov/pubmed/34622874
http://dx.doi.org/10.1097/MD.0000000000027468
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author Zhang, Lu-kai
Zhu, Fang-bing
Gao, Huan-huan
Zhang, Lei
Quan, Ren-fu
author_facet Zhang, Lu-kai
Zhu, Fang-bing
Gao, Huan-huan
Zhang, Lei
Quan, Ren-fu
author_sort Zhang, Lu-kai
collection PubMed
description BACKGROUND: Effective postoperative analgesia is of great significance for postoperative rehabilitation. This meta-analysis aimed to investigate the efficacy of corticosteroid on pain following total joint arthroplasty. METHOD: PubMed (1996–December 2020), Embase (1996–December 2020), and the Cochrane Library (CENTRAL, December 2020) were searched and a total of 11 randomized controlled trials met our inclusion criteria. RESULTS: Eleven randomized controlled trials met the inclusion criteria. Pooled data indicated the corticosteroid group was effective compared to the control group in terms of the visual analogue scale at rest (P < .05) and movement (P < .05), the total morphine equivalent consumption (P < .05), and the length of stay (P < .05), without increasing the risk of periprosthetic joint infection (P = .74) and the length of stay (P = .32). CONCLUSIONS: Compared to the control group, intraoperative corticosteroid was benefit to the pain management in total joint arthroplasty.
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spelling pubmed-85006262021-10-12 Is intraoperative corticosteroid a good choice for postoperative pain relief in total joint arthroplasty? A meta-analysis of 11 randomized controlled trials Zhang, Lu-kai Zhu, Fang-bing Gao, Huan-huan Zhang, Lei Quan, Ren-fu Medicine (Baltimore) 7100 BACKGROUND: Effective postoperative analgesia is of great significance for postoperative rehabilitation. This meta-analysis aimed to investigate the efficacy of corticosteroid on pain following total joint arthroplasty. METHOD: PubMed (1996–December 2020), Embase (1996–December 2020), and the Cochrane Library (CENTRAL, December 2020) were searched and a total of 11 randomized controlled trials met our inclusion criteria. RESULTS: Eleven randomized controlled trials met the inclusion criteria. Pooled data indicated the corticosteroid group was effective compared to the control group in terms of the visual analogue scale at rest (P < .05) and movement (P < .05), the total morphine equivalent consumption (P < .05), and the length of stay (P < .05), without increasing the risk of periprosthetic joint infection (P = .74) and the length of stay (P = .32). CONCLUSIONS: Compared to the control group, intraoperative corticosteroid was benefit to the pain management in total joint arthroplasty. Lippincott Williams & Wilkins 2021-10-08 /pmc/articles/PMC8500626/ /pubmed/34622874 http://dx.doi.org/10.1097/MD.0000000000027468 Text en Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/)
spellingShingle 7100
Zhang, Lu-kai
Zhu, Fang-bing
Gao, Huan-huan
Zhang, Lei
Quan, Ren-fu
Is intraoperative corticosteroid a good choice for postoperative pain relief in total joint arthroplasty? A meta-analysis of 11 randomized controlled trials
title Is intraoperative corticosteroid a good choice for postoperative pain relief in total joint arthroplasty? A meta-analysis of 11 randomized controlled trials
title_full Is intraoperative corticosteroid a good choice for postoperative pain relief in total joint arthroplasty? A meta-analysis of 11 randomized controlled trials
title_fullStr Is intraoperative corticosteroid a good choice for postoperative pain relief in total joint arthroplasty? A meta-analysis of 11 randomized controlled trials
title_full_unstemmed Is intraoperative corticosteroid a good choice for postoperative pain relief in total joint arthroplasty? A meta-analysis of 11 randomized controlled trials
title_short Is intraoperative corticosteroid a good choice for postoperative pain relief in total joint arthroplasty? A meta-analysis of 11 randomized controlled trials
title_sort is intraoperative corticosteroid a good choice for postoperative pain relief in total joint arthroplasty? a meta-analysis of 11 randomized controlled trials
topic 7100
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500626/
https://www.ncbi.nlm.nih.gov/pubmed/34622874
http://dx.doi.org/10.1097/MD.0000000000027468
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