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Long-term impact of olfactory dysfunction on daily life
BACKGROUND: Olfactory dysfunction (OD) is common in the general population, affects the quality of life (QoL), and is suspected to cause depression. Long-term outcome data are lacking and there is a need to improve patient counselling regarding prognosis. We aimed to assess subjective long-term reco...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer Vienna
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500863/ https://www.ncbi.nlm.nih.gov/pubmed/33084955 http://dx.doi.org/10.1007/s00508-020-01751-5 |
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author | Auinger, Alice B. Besser, Gerold Liu, David T. Renner, Bertold Mueller, Christian A. |
author_facet | Auinger, Alice B. Besser, Gerold Liu, David T. Renner, Bertold Mueller, Christian A. |
author_sort | Auinger, Alice B. |
collection | PubMed |
description | BACKGROUND: Olfactory dysfunction (OD) is common in the general population, affects the quality of life (QoL), and is suspected to cause depression. Long-term outcome data are lacking and there is a need to improve patient counselling regarding prognosis. We aimed to assess subjective long-term recovery rates, the QoL, and mood disturbance in a group of 65 patients, who were affected with OD. METHODS: Out of 325 patients treated for OD between 2003 and 2009 at a smell and taste clinic, 65 patients were included for a follow-up after an average of 8.6 years. A total of 28 patients answered questionnaires only and 37 patients were provided with an additional smell identification test. Among others, questionnaires included a short form of the World Health Organization quality of life questionnaire (WHOQOL-BREF) and the Beck’s depression inventory. RESULTS: In the long run, subjective improvement was stated in 33.8% of all patients, with the highest rate of 42.3% in patients with postinfectious OD. The subjective rating of olfactory function on a visual analogue scale was significantly higher at study follow-up compared to first clinical contact (median 1.25 vs. 4.5; U = 469.5, p = 0.001), as were mean identification scores (6.0 ± 3.0 vs. 8.0 ± 4.0, t(18) = 2.51, p = 0.021). The QoL in general was considered reduced in 40% of all patients at follow-up. Furthermore, participants exhibited only minor, if any, depressive symptoms. CONCLUSION: Despite negative effects of OD on certain activities in daily life, such as cooking, detecting spoiled food, or personal hygiene, it seems that the patients included in this study adapted to the OD in the long-term. The current findings should aid clinicians in patient counselling. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s00508-020-01751-5) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-8500863 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Springer Vienna |
record_format | MEDLINE/PubMed |
spelling | pubmed-85008632021-10-19 Long-term impact of olfactory dysfunction on daily life Auinger, Alice B. Besser, Gerold Liu, David T. Renner, Bertold Mueller, Christian A. Wien Klin Wochenschr Original Article BACKGROUND: Olfactory dysfunction (OD) is common in the general population, affects the quality of life (QoL), and is suspected to cause depression. Long-term outcome data are lacking and there is a need to improve patient counselling regarding prognosis. We aimed to assess subjective long-term recovery rates, the QoL, and mood disturbance in a group of 65 patients, who were affected with OD. METHODS: Out of 325 patients treated for OD between 2003 and 2009 at a smell and taste clinic, 65 patients were included for a follow-up after an average of 8.6 years. A total of 28 patients answered questionnaires only and 37 patients were provided with an additional smell identification test. Among others, questionnaires included a short form of the World Health Organization quality of life questionnaire (WHOQOL-BREF) and the Beck’s depression inventory. RESULTS: In the long run, subjective improvement was stated in 33.8% of all patients, with the highest rate of 42.3% in patients with postinfectious OD. The subjective rating of olfactory function on a visual analogue scale was significantly higher at study follow-up compared to first clinical contact (median 1.25 vs. 4.5; U = 469.5, p = 0.001), as were mean identification scores (6.0 ± 3.0 vs. 8.0 ± 4.0, t(18) = 2.51, p = 0.021). The QoL in general was considered reduced in 40% of all patients at follow-up. Furthermore, participants exhibited only minor, if any, depressive symptoms. CONCLUSION: Despite negative effects of OD on certain activities in daily life, such as cooking, detecting spoiled food, or personal hygiene, it seems that the patients included in this study adapted to the OD in the long-term. The current findings should aid clinicians in patient counselling. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s00508-020-01751-5) contains supplementary material, which is available to authorized users. Springer Vienna 2020-10-21 2021 /pmc/articles/PMC8500863/ /pubmed/33084955 http://dx.doi.org/10.1007/s00508-020-01751-5 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Original Article Auinger, Alice B. Besser, Gerold Liu, David T. Renner, Bertold Mueller, Christian A. Long-term impact of olfactory dysfunction on daily life |
title | Long-term impact of olfactory dysfunction on daily life |
title_full | Long-term impact of olfactory dysfunction on daily life |
title_fullStr | Long-term impact of olfactory dysfunction on daily life |
title_full_unstemmed | Long-term impact of olfactory dysfunction on daily life |
title_short | Long-term impact of olfactory dysfunction on daily life |
title_sort | long-term impact of olfactory dysfunction on daily life |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500863/ https://www.ncbi.nlm.nih.gov/pubmed/33084955 http://dx.doi.org/10.1007/s00508-020-01751-5 |
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