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Idiopathic and acquired pedophilia as two distinct disorders: an insight from neuroimaging
Pedophilia is a disorder of public concern because of its association with child sexual offense and recidivism. Previous neuroimaging studies of potential brain abnormalities underlying pedophilic behavior, either in idiopathic or acquired (i.e., emerging following brain damages) pedophilia, led to...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500885/ https://www.ncbi.nlm.nih.gov/pubmed/33507519 http://dx.doi.org/10.1007/s11682-020-00442-z |
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author | Scarpazza, Cristina Finos, Livio Genon, Sarah Masiero, Laura Bortolato, Elena Cavaliere, Camilla Pezzaioli, Jessica Monaro, Merylin Navarin, Nicolò Battaglia, Umberto Pietrini, Pietro Ferracuti, Stefano Sartori, Giuseppe Camperio Ciani, Andrea S. |
author_facet | Scarpazza, Cristina Finos, Livio Genon, Sarah Masiero, Laura Bortolato, Elena Cavaliere, Camilla Pezzaioli, Jessica Monaro, Merylin Navarin, Nicolò Battaglia, Umberto Pietrini, Pietro Ferracuti, Stefano Sartori, Giuseppe Camperio Ciani, Andrea S. |
author_sort | Scarpazza, Cristina |
collection | PubMed |
description | Pedophilia is a disorder of public concern because of its association with child sexual offense and recidivism. Previous neuroimaging studies of potential brain abnormalities underlying pedophilic behavior, either in idiopathic or acquired (i.e., emerging following brain damages) pedophilia, led to inconsistent results. This study sought to explore the neural underpinnings of pedophilic behavior and to determine the extent to which brain alterations may be related to distinct psychopathological features in pedophilia. To this aim, we run a coordinate based meta-analysis on previously published papers reporting whole brain analysis and a lesion network analysis, using brain lesions as seeds in a resting state connectivity analysis. The behavioral profiling approach was applied to link identified regions with the corresponding psychological processes. While no consistent neuroanatomical alterations were identified in idiopathic pedophilia, the current results support that all the lesions causing acquired pedophilia are localized within a shared resting state network that included posterior midlines structures, right inferior temporal gyrus and bilateral orbitofrontal cortex. These regions are associated with action inhibition and social cognition, abilities that are consistently and severely impaired in acquired pedophiles. This study suggests that idiopathic and acquired pedophilia may be two distinct disorders, in line with their distinctive clinical features, including age of onset, reversibility and modus operandi. Understanding the neurobiological underpinnings of pedophilic behavior may contribute to a more comprehensive characterization of these individuals on a clinical ground, a pivotal step forward for the development of more efficient therapeutic rehabilitation strategies. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s11682-020-00442-z. |
format | Online Article Text |
id | pubmed-8500885 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-85008852021-10-19 Idiopathic and acquired pedophilia as two distinct disorders: an insight from neuroimaging Scarpazza, Cristina Finos, Livio Genon, Sarah Masiero, Laura Bortolato, Elena Cavaliere, Camilla Pezzaioli, Jessica Monaro, Merylin Navarin, Nicolò Battaglia, Umberto Pietrini, Pietro Ferracuti, Stefano Sartori, Giuseppe Camperio Ciani, Andrea S. Brain Imaging Behav Review Article Pedophilia is a disorder of public concern because of its association with child sexual offense and recidivism. Previous neuroimaging studies of potential brain abnormalities underlying pedophilic behavior, either in idiopathic or acquired (i.e., emerging following brain damages) pedophilia, led to inconsistent results. This study sought to explore the neural underpinnings of pedophilic behavior and to determine the extent to which brain alterations may be related to distinct psychopathological features in pedophilia. To this aim, we run a coordinate based meta-analysis on previously published papers reporting whole brain analysis and a lesion network analysis, using brain lesions as seeds in a resting state connectivity analysis. The behavioral profiling approach was applied to link identified regions with the corresponding psychological processes. While no consistent neuroanatomical alterations were identified in idiopathic pedophilia, the current results support that all the lesions causing acquired pedophilia are localized within a shared resting state network that included posterior midlines structures, right inferior temporal gyrus and bilateral orbitofrontal cortex. These regions are associated with action inhibition and social cognition, abilities that are consistently and severely impaired in acquired pedophiles. This study suggests that idiopathic and acquired pedophilia may be two distinct disorders, in line with their distinctive clinical features, including age of onset, reversibility and modus operandi. Understanding the neurobiological underpinnings of pedophilic behavior may contribute to a more comprehensive characterization of these individuals on a clinical ground, a pivotal step forward for the development of more efficient therapeutic rehabilitation strategies. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s11682-020-00442-z. Springer US 2021-01-28 2021 /pmc/articles/PMC8500885/ /pubmed/33507519 http://dx.doi.org/10.1007/s11682-020-00442-z Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Review Article Scarpazza, Cristina Finos, Livio Genon, Sarah Masiero, Laura Bortolato, Elena Cavaliere, Camilla Pezzaioli, Jessica Monaro, Merylin Navarin, Nicolò Battaglia, Umberto Pietrini, Pietro Ferracuti, Stefano Sartori, Giuseppe Camperio Ciani, Andrea S. Idiopathic and acquired pedophilia as two distinct disorders: an insight from neuroimaging |
title | Idiopathic and acquired pedophilia as two distinct disorders: an insight from neuroimaging |
title_full | Idiopathic and acquired pedophilia as two distinct disorders: an insight from neuroimaging |
title_fullStr | Idiopathic and acquired pedophilia as two distinct disorders: an insight from neuroimaging |
title_full_unstemmed | Idiopathic and acquired pedophilia as two distinct disorders: an insight from neuroimaging |
title_short | Idiopathic and acquired pedophilia as two distinct disorders: an insight from neuroimaging |
title_sort | idiopathic and acquired pedophilia as two distinct disorders: an insight from neuroimaging |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500885/ https://www.ncbi.nlm.nih.gov/pubmed/33507519 http://dx.doi.org/10.1007/s11682-020-00442-z |
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