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The regulatory landscape of the human HPF1- and ARH3-dependent ADP-ribosylome

Despite the involvement of Poly(ADP-ribose) polymerase-1 (PARP1) in many important biological pathways, the target residues of PARP1-mediated ADP-ribosylation remain ambiguous. To explicate the ADP-ribosylation regulome, we analyze human cells depleted for key regulators of PARP1 activity, histone P...

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Detalles Bibliográficos
Autores principales: Hendriks, Ivo A., Buch-Larsen, Sara C., Prokhorova, Evgeniia, Elsborg, Jonas D., Rebak, Alexandra K.L.F.S., Zhu, Kang, Ahel, Dragana, Lukas, Claudia, Ahel, Ivan, Nielsen, Michael L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501107/
https://www.ncbi.nlm.nih.gov/pubmed/34625544
http://dx.doi.org/10.1038/s41467-021-26172-4