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Relationship of ventral striatum activation during effort discounting to clinical amotivation severity in schizophrenia

Motivational deficits play a central role in disability due to negative symptoms of schizophrenia (SZ), but limited pathophysiological understanding impedes critically needed therapeutic development. We applied an fMRI Effort Discounting Task (EDT) that quantifies motivation using a neuroeconomic de...

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Detalles Bibliográficos
Autores principales:	Prettyman, Greer E., Kable, Joseph W., Didier, Paige, Shankar, Sheila, Satterthwaite, Theodore D., Davatzikos, Christos, Bilker, Warren B., Elliott, Mark A., Ruparel, Kosha, Wolf, Daniel H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501117/ https://www.ncbi.nlm.nih.gov/pubmed/34625567 http://dx.doi.org/10.1038/s41537-021-00178-9

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