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Optimization of Metabolic Oligosaccharide Engineering with Ac(4)GalNAlk and Ac(4)GlcNAlk by an Engineered Pyrophosphorylase
[Image: see text] Metabolic oligosaccharide engineering (MOE) has fundamentally contributed to our understanding of protein glycosylation. Efficient MOE reagents are activated into nucleotide-sugars by cellular biosynthetic machineries, introduced into glycoproteins and traceable by bioorthogonal ch...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501146/ https://www.ncbi.nlm.nih.gov/pubmed/33835779 http://dx.doi.org/10.1021/acschembio.1c00034 |