Cargando…

Optimization of Metabolic Oligosaccharide Engineering with Ac(4)GalNAlk and Ac(4)GlcNAlk by an Engineered Pyrophosphorylase

[Image: see text] Metabolic oligosaccharide engineering (MOE) has fundamentally contributed to our understanding of protein glycosylation. Efficient MOE reagents are activated into nucleotide-sugars by cellular biosynthetic machineries, introduced into glycoproteins and traceable by bioorthogonal ch...

Descripción completa

Detalles Bibliográficos
Autores principales: Cioce, Anna, Bineva-Todd, Ganka, Agbay, Anthony J., Choi, Junwon, Wood, Thomas M., Debets, Marjoke F., Browne, William M., Douglas, Holly L., Roustan, Chloe, Tastan, Omur Y., Kjaer, Svend, Bush, Jacob T., Bertozzi, Carolyn R., Schumann, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501146/
https://www.ncbi.nlm.nih.gov/pubmed/33835779
http://dx.doi.org/10.1021/acschembio.1c00034