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Optimization of Metabolic Oligosaccharide Engineering with Ac(4)GalNAlk and Ac(4)GlcNAlk by an Engineered Pyrophosphorylase
[Image: see text] Metabolic oligosaccharide engineering (MOE) has fundamentally contributed to our understanding of protein glycosylation. Efficient MOE reagents are activated into nucleotide-sugars by cellular biosynthetic machineries, introduced into glycoproteins and traceable by bioorthogonal ch...
Autores principales: | Cioce, Anna, Bineva-Todd, Ganka, Agbay, Anthony J., Choi, Junwon, Wood, Thomas M., Debets, Marjoke F., Browne, William M., Douglas, Holly L., Roustan, Chloe, Tastan, Omur Y., Kjaer, Svend, Bush, Jacob T., Bertozzi, Carolyn R., Schumann, Benjamin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2021
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501146/ https://www.ncbi.nlm.nih.gov/pubmed/33835779 http://dx.doi.org/10.1021/acschembio.1c00034 |
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