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Ovarian reserve of women with and without BRCA pathogenic variants: A systematic review and meta-analysis

INTRODUCTION: Preliminary clinical evidence suggests a detrimental effect of pathogenic variants of BRCA1 and 2 genes on fertility outcome. This meta-analysis evaluates whether women carrying BRCA mutations (BRCAm) have decreased ovarian reserve, in terms of Anti-Muellerian Hormone (AMH), compared t...

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Detalles Bibliográficos
Autores principales: Gasparri, Maria Luisa, Di Micco, Rosa, Zuber, Veronica, Taghavi, Katayoun, Bianchini, Giampaolo, Bellaminutti, Serena, Meani, Francesco, Graffeo, Rossella, Candiani, Massimo, Mueller, Michael D., Papadia, Andrea, Gentilini, Oreste D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501498/
https://www.ncbi.nlm.nih.gov/pubmed/34627117
http://dx.doi.org/10.1016/j.breast.2021.09.006