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Folate metabolism modifies chromosomal damage induced by 1,3-butadiene: results from a match-up study in China and in vitro experiments

OBJECTIVES: To explore the role of folate metabolism in 1,3-Butadiene (BD)'s genotoxicity, we conducted a match-up study in BD-exposed workers in China to analyze the associations between the polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and the chromosomal damage induced by BD e...

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Detalles Bibliográficos
Autores principales: Xiang, Menglong, Wang, Zhi, Zou, Peng, Ling, Xi, Zhang, Guowei, Zhou, Ziyuan, Cao, Jia, Ao, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501532/
https://www.ncbi.nlm.nih.gov/pubmed/34627392
http://dx.doi.org/10.1186/s41021-021-00217-y