Potential for treatment benefit of STING agonists plus immune checkpoint inhibitors in oral squamous cell carcinoma

BACKGROUND: DNA-sensing receptor cyclic GMP–AMP synthase (cGAS) and its downstream signaling effector stimulator of interferon genes (STING) present a novel role in anti-tumor immunity. Recently, the combination of cGAS-STING agonists and immunotherapy achieved promising results in some tumor types....

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Detalles Bibliográficos
Autores principales: Zhu, Chao, Li, Jiang, Yao, Mianfeng, Fang, Changyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501566/
https://www.ncbi.nlm.nih.gov/pubmed/34625078
http://dx.doi.org/10.1186/s12903-021-01813-8

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