Cargando…

Microbiome study in irradiated mice treated with BIO 300, a promising radiation countermeasure

BACKGROUND: The mammalian gut harbors very complex and diverse microbiota that play an important role in intestinal homeostasis and host health. Exposure to radiation results in dysbiosis of the gut microbiota leading to detrimental pathophysiological changes to the host. To alleviate the effects of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cheema, Amrita K., Li, Yaoxiang, Singh, Jatinder, Johnson, Ryan, Girgis, Michael, Wise, Stephen Y., Fatanmi, Oluseyi O., Kaytor, Michael D., Singh, Vijay K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501697/ https://www.ncbi.nlm.nih.gov/pubmed/34627406 http://dx.doi.org/10.1186/s42523-021-00132-1

Ejemplares similares

Comparative proteomic analysis of serum from nonhuman primates administered BIO 300: a promising radiation countermeasure
por: Girgis, Michael, et al.
Publicado: (2020)

Analysis of the metabolomic profile in serum of irradiated nonhuman primates treated with Ex-Rad, a radiation countermeasure
por: Li, Yaoxiang, et al.
Publicado: (2021)

Pharmacokinetic and Metabolomic Studies with BIO 300, a Nanosuspension of Genistein, in a Nonhuman Primate Model
por: Cheema, Amrita K., et al.
Publicado: (2019)

Analysis of the Proteomic Profile in Serum of Irradiated Nonhuman Primates Treated with Ex-Rad, a Radiation Medical Countermeasure
por: Carpenter, Alana D., et al.
Publicado: (2023)

Pharmacokinetic and metabolomic studies with a BIO 300 Oral Powder formulation in nonhuman primates
por: Li, Yaoxiang, et al.
Publicado: (2022)

Transcriptome of rhesus macaque (Macaca mulatta) exposed to total-body irradiation
por: Li, Yaoxiang, et al.
Publicado: (2021)

A Metabolomic and Lipidomic Serum Signature from Nonhuman Primates Administered with a Promising Radiation Countermeasure, Gamma-Tocotrienol
por: Cheema, Amrita K., et al.
Publicado: (2017)

Alterations in Tissue Metabolite Profiles with Amifostine-Prophylaxed Mice Exposed to Gamma Radiation
por: Cheema, Amrita K., et al.
Publicado: (2020)

Gamma-tocotrienol, a radiation countermeasure, reverses proteomic changes in serum following total-body gamma irradiation in mice
por: Rosen, Elliot, et al.
Publicado: (2022)

Progenitor Cell Mobilization by Gamma-tocotrienol: A Promising Radiation Countermeasure
por: Singh, Vijay K., et al.
Publicado: (2016)

THE POTENTIATION OF THE RADIOPROTECTIVE EFFICACY OF TWO MEDICAL COUNTERMEASURES, GAMMA-TOCOTRIENOL AND AMIFOSTINE, BY A COMBINATION PROPHYLACTIC MODALITY
por: Singh, Vijay K., et al.
Publicado: (2016)

Progenitors Mobilized by Gamma-Tocotrienol as an Effective Radiation Countermeasure
por: Singh, Vijay K., et al.
Publicado: (2014)

Lung transcriptome of nonhuman primates exposed to total- and partial-body irradiation
por: Vellichirammal, Neetha Nanoth, et al.
Publicado: (2022)

Metabolomic Studies of Tissue Injury in Nonhuman Primates Exposed to Gamma-Radiation
por: Cheema, Amrita K., et al.
Publicado: (2019)

Radioprotective properties of tocopherol succinate against ionizing radiation in mice
por: Singh, Vijay K., et al.
Publicado: (2013)

Metabolomic studies in tissues of mice treated with amifostine and exposed to gamma-radiation
por: Cheema, Amrita K., et al.
Publicado: (2019)

Plasma Derived Exosomal Biomarkers of Exposure to Ionizing Radiation in Nonhuman Primates
por: Cheema, Amrita K., et al.
Publicado: (2018)

γ-Tocotrienol as a Promising Countermeasure for Acute Radiation Syndrome: Current Status
por: Singh, Vijay K., et al.
Publicado: (2016)

Effects of Gamma-Tocotrienol on Partial-Body Irradiation-Induced Intestinal Injury in a Nonhuman Primate Model
por: Garg, Sarita, et al.
Publicado: (2022)

Gamma-Tocotrienol Modulates Total-Body Irradiation-Induced Hematopoietic Injury in a Nonhuman Primate Model
por: Garg, Tarun K., et al.
Publicado: (2022)

Plasma-derived extracellular vesicles yield predictive markers of cranial irradiation exposure in mice
por: Hinzman, Charles P., et al.
Publicado: (2019)

Radiation countermeasure agents: an update (2011 – 2014)
por: Singh, Vijay K, et al.
Publicado: (2014)

Alpha-tocopherol succinate- and AMD3100-mobilized progenitors mitigate radiation combined injury in mice
por: Singh, Vijay K., et al.
Publicado: (2014)

A multi‐omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells
por: Hinzman, Charles P., et al.
Publicado: (2022)

Transcriptome profile changes in the jejunum of nonhuman primates exposed to supralethal dose of total- or partial-body radiation
por: Vellichirammal, Neetha Nanoth, et al.
Publicado: (2023)

Effects of Whole and Partial Heart Irradiation on Collagen, Mast Cells, and Toll-like Receptor 4 in the Mouse Heart
por: Sridharan, Vijayalakshmi, et al.
Publicado: (2023)

Medical countermeasures for unwanted CBRN exposures: part II radiological and nuclear threats with review of recent countermeasure patents
por: Singh, Vijay K., et al.
Publicado: (2016)

Vitamin E: tocopherols and tocotrienols as potential radiation countermeasures
por: Singh, Vijay K., et al.
Publicado: (2013)

Biologics as countermeasures for acute radiation syndrome: where are we now?
por: Singh, Vijay K, et al.
Publicado: (2015)

Effects of Gamma-Tocotrienol on Intestinal Injury in a GI-Specific Acute Radiation Syndrome Model in Nonhuman Primate
por: Garg, Sarita, et al.
Publicado: (2022)

Patents for Toll-like receptor ligands as radiation countermeasures for acute radiation syndrome
por: Singh, Vijay K, et al.
Publicado: (2015)

Use of biomarkers for assessing radiation injury and efficacy of countermeasures
por: Singh, Vijay K, et al.
Publicado: (2016)

Use of BioSense for Rapid Assessment of the Safety of Medical Countermeasures
por: Coates, Ralph J., et al.
Publicado: (2013)

Combined immunomodulator and antimicrobial therapy eliminates polymicrobial sepsis and modulates cytokine production in combined injured mice
por: Elliott, Thomas B., et al.
Publicado: (2015)

An efficient drug delivery vehicle for botulism countermeasure
por: Zhang, Peng, et al.
Publicado: (2009)

4287 Extracellular vesicles as biomarkers for early detection of pancreatic cancer
por: Hinzman, Charles P, et al.
Publicado: (2020)

NF-kB as a key player in regulation of cellular radiation responses and identification of radiation countermeasures
por: Singh, Vijay, et al.
Publicado: (2015)

Medical Countermeasures for Radiation Exposure and Related Injuries: Characterization of Medicines, FDA-Approval Status and Inclusion into the Strategic National Stockpile
por: Singh, Vijay K., et al.
Publicado: (2015)

Endurance Exercise as a Countermeasure for Aging
por: Lanza, Ian R., et al.
Publicado: (2008)

68477 Pancreatic cancer cell extracellular vesicles drive the unfolded protein response in recipient normal pancreatic cells.
por: Hinzman, Charles, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_9os1877cl8unq154fg55too474