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Excipient of paclitaxel induces metabolic dysregulation and unfolded protein response

Taxane-based reagents, such as Taxol, Taxotere, and Abraxane, are popular anti-cancer drugs that can differ in their clinical efficacy. This difference is generally attributed to their active pharmaceutical ingredients. Here, we report a serendipitous discovery that Taxol induces metabolic dysregula...

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Detalles Bibliográficos
Autores principales:	Dai, Qian, Liu, Xiaolin, He, Tao, Yang, Chao, Jiang, Jinfeng, Fang, Yin, Fu, Zhoukai, Yuan, Yuan, Bai, Shujun, Qiu, Tong, Yin, Rutie, Ding, Ping, Chen, Jie, Li, Qintong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501768/ https://www.ncbi.nlm.nih.gov/pubmed/34646996 http://dx.doi.org/10.1016/j.isci.2021.103170

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