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Risk-benefit assessment of major versus minor osteotomies for flexible and rigid cervical deformity correction
INTRODUCTION: Osteotomies are commonly performed to correct sagittal malalignment in cervical deformity (CD). However, the risks and benefits of performing a major osteotomy for cervical deformity correction have been understudied. The objective of this retrospective cohort study was to investigate...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501816/ https://www.ncbi.nlm.nih.gov/pubmed/34728993 http://dx.doi.org/10.4103/jcvjs.jcvjs_35_21 |
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author | Passias, Peter Gust Passfall, Lara Horn, Samantha R. Pierce, Katherine E. Lafage, Virginie Lafage, Renaud Smith, Justin S. Line, Breton G. Mundis, Gregory M. Eastlack, Robert Diebo, Bassel G. Protopsaltis, Themistocles S. Kim, Han Jo Scheer, Justin Burton, Douglas C. Hart, Robert A. Schwab, Frank J. Bess, Shay Ames, Christopher P. Shaffrey, Christopher I. |
author_facet | Passias, Peter Gust Passfall, Lara Horn, Samantha R. Pierce, Katherine E. Lafage, Virginie Lafage, Renaud Smith, Justin S. Line, Breton G. Mundis, Gregory M. Eastlack, Robert Diebo, Bassel G. Protopsaltis, Themistocles S. Kim, Han Jo Scheer, Justin Burton, Douglas C. Hart, Robert A. Schwab, Frank J. Bess, Shay Ames, Christopher P. Shaffrey, Christopher I. |
author_sort | Passias, Peter Gust |
collection | PubMed |
description | INTRODUCTION: Osteotomies are commonly performed to correct sagittal malalignment in cervical deformity (CD). However, the risks and benefits of performing a major osteotomy for cervical deformity correction have been understudied. The objective of this retrospective cohort study was to investigate the risks and benefits of performing a major osteotomy for CD correction. METHODS: Patients stratified based on major osteotomy (MAJ) or minor (MIN). Independent t-tests and Chi-squared tests were used to assess differences between MAJ and MIN. A sub-analysis compared patients with flexible versus rigid CL. RESULTS: 137 CD patients were included (62 years, 65% F). 19.0% CD patients underwent a MAJ osteotomy. After propensity score matching for cSVA, 52 patients were included. About 19.0% CD patients underwent a MAJ osteotomy. MAJ patients had more minor complications (P = 0.045), despite similar surgical outcomes as MIN. At 3M, MAJ and MIN patients had similar NDI, mJOA, and EQ5D scores, however by 1 year, MAJ patients reached MCID for NDI less than MIN patients (P = 0.003). MAJ patients with rigid deformities had higher rates of complications (79% vs. 29%, P = 0.056) and were less likely to show improvement in NDI at 1 year (0.95 vs. 0.54, P = 0.027). Both groups had similar sagittal realignment at 1 year (all P > 0.05). CONCLUSIONS: Cervical deformity patients who underwent a major osteotomy had similar clinical outcomes at 3-months but worse outcomes at 1-year as compared to minor osteotomies, likely due to differences in baseline deformity. Patients with rigid deformities who underwent a major osteotomy had higher complication rates and worse clinical improvement despite similar realignment at 1 year. |
format | Online Article Text |
id | pubmed-8501816 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-85018162021-11-01 Risk-benefit assessment of major versus minor osteotomies for flexible and rigid cervical deformity correction Passias, Peter Gust Passfall, Lara Horn, Samantha R. Pierce, Katherine E. Lafage, Virginie Lafage, Renaud Smith, Justin S. Line, Breton G. Mundis, Gregory M. Eastlack, Robert Diebo, Bassel G. Protopsaltis, Themistocles S. Kim, Han Jo Scheer, Justin Burton, Douglas C. Hart, Robert A. Schwab, Frank J. Bess, Shay Ames, Christopher P. Shaffrey, Christopher I. J Craniovertebr Junction Spine Original Article INTRODUCTION: Osteotomies are commonly performed to correct sagittal malalignment in cervical deformity (CD). However, the risks and benefits of performing a major osteotomy for cervical deformity correction have been understudied. The objective of this retrospective cohort study was to investigate the risks and benefits of performing a major osteotomy for CD correction. METHODS: Patients stratified based on major osteotomy (MAJ) or minor (MIN). Independent t-tests and Chi-squared tests were used to assess differences between MAJ and MIN. A sub-analysis compared patients with flexible versus rigid CL. RESULTS: 137 CD patients were included (62 years, 65% F). 19.0% CD patients underwent a MAJ osteotomy. After propensity score matching for cSVA, 52 patients were included. About 19.0% CD patients underwent a MAJ osteotomy. MAJ patients had more minor complications (P = 0.045), despite similar surgical outcomes as MIN. At 3M, MAJ and MIN patients had similar NDI, mJOA, and EQ5D scores, however by 1 year, MAJ patients reached MCID for NDI less than MIN patients (P = 0.003). MAJ patients with rigid deformities had higher rates of complications (79% vs. 29%, P = 0.056) and were less likely to show improvement in NDI at 1 year (0.95 vs. 0.54, P = 0.027). Both groups had similar sagittal realignment at 1 year (all P > 0.05). CONCLUSIONS: Cervical deformity patients who underwent a major osteotomy had similar clinical outcomes at 3-months but worse outcomes at 1-year as compared to minor osteotomies, likely due to differences in baseline deformity. Patients with rigid deformities who underwent a major osteotomy had higher complication rates and worse clinical improvement despite similar realignment at 1 year. Wolters Kluwer - Medknow 2021 2021-09-08 /pmc/articles/PMC8501816/ /pubmed/34728993 http://dx.doi.org/10.4103/jcvjs.jcvjs_35_21 Text en Copyright: © 2021 Journal of Craniovertebral Junction and Spine https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Passias, Peter Gust Passfall, Lara Horn, Samantha R. Pierce, Katherine E. Lafage, Virginie Lafage, Renaud Smith, Justin S. Line, Breton G. Mundis, Gregory M. Eastlack, Robert Diebo, Bassel G. Protopsaltis, Themistocles S. Kim, Han Jo Scheer, Justin Burton, Douglas C. Hart, Robert A. Schwab, Frank J. Bess, Shay Ames, Christopher P. Shaffrey, Christopher I. Risk-benefit assessment of major versus minor osteotomies for flexible and rigid cervical deformity correction |
title | Risk-benefit assessment of major versus minor osteotomies for flexible and rigid cervical deformity correction |
title_full | Risk-benefit assessment of major versus minor osteotomies for flexible and rigid cervical deformity correction |
title_fullStr | Risk-benefit assessment of major versus minor osteotomies for flexible and rigid cervical deformity correction |
title_full_unstemmed | Risk-benefit assessment of major versus minor osteotomies for flexible and rigid cervical deformity correction |
title_short | Risk-benefit assessment of major versus minor osteotomies for flexible and rigid cervical deformity correction |
title_sort | risk-benefit assessment of major versus minor osteotomies for flexible and rigid cervical deformity correction |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501816/ https://www.ncbi.nlm.nih.gov/pubmed/34728993 http://dx.doi.org/10.4103/jcvjs.jcvjs_35_21 |
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