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Intramedullary spinal cord tumors: A retrospective multicentric study

CONTEXT: Intramedullary tumors are neoformations taking part on the spinal cord, and they are a rare pathology. Due to the rarity of such lesions, clinical studies take years to ensure a decent feedback with a significant number of cases. DESIGN: Our study is retrospective and descriptive. PARTICIPA...

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Autores principales: Hachicha, Anis, Belhaj, Ala, Karmeni, Nadhir, Slimane, Abdelhafidh, Bouali, Sofiene, Kallel, Jalel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501820/
https://www.ncbi.nlm.nih.gov/pubmed/34728994
http://dx.doi.org/10.4103/jcvjs.jcvjs_64_21
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author Hachicha, Anis
Belhaj, Ala
Karmeni, Nadhir
Slimane, Abdelhafidh
Bouali, Sofiene
Kallel, Jalel
author_facet Hachicha, Anis
Belhaj, Ala
Karmeni, Nadhir
Slimane, Abdelhafidh
Bouali, Sofiene
Kallel, Jalel
author_sort Hachicha, Anis
collection PubMed
description CONTEXT: Intramedullary tumors are neoformations taking part on the spinal cord, and they are a rare pathology. Due to the rarity of such lesions, clinical studies take years to ensure a decent feedback with a significant number of cases. DESIGN: Our study is retrospective and descriptive. PARTICIPANTS: We share a Tunisian multicentric experience of 27 years through a retrospective study of 120 cases of spinal cord tumors that have been operated in six different centers. OUTCOME MEASURES: The clinical, radiological, and histological findings have been analyzed along with postoperative results and tumoral progression so that we could conclude to some factors of prognosis concerning the management of these tumors. RESULTS: The mean age of our patients is 33.84 years. We had 57 males and 63 females. The most frequent revealing symptom was motor trouble presented as frequent as 77.5% of the patients. Glial tumors were represented in 81 of the cases (67.5%) and nonglial by 39 cases (32.5%). Glial tumors we found were essentially 39 ependymomas and 35 astrocytomas. Surgical resection is key in the management of these lesions; the quality of tumoral resection was a significant factor of disease progression as subtotal resection is correlated to more important progression than total one. CONCLUSION: We conclude this work with some statements. In terms of functional results, age is not a significant factor. Presurgical functional state, the histological type, and the extent of surgical resection are the important factors.
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spelling pubmed-85018202021-11-01 Intramedullary spinal cord tumors: A retrospective multicentric study Hachicha, Anis Belhaj, Ala Karmeni, Nadhir Slimane, Abdelhafidh Bouali, Sofiene Kallel, Jalel J Craniovertebr Junction Spine Original Article CONTEXT: Intramedullary tumors are neoformations taking part on the spinal cord, and they are a rare pathology. Due to the rarity of such lesions, clinical studies take years to ensure a decent feedback with a significant number of cases. DESIGN: Our study is retrospective and descriptive. PARTICIPANTS: We share a Tunisian multicentric experience of 27 years through a retrospective study of 120 cases of spinal cord tumors that have been operated in six different centers. OUTCOME MEASURES: The clinical, radiological, and histological findings have been analyzed along with postoperative results and tumoral progression so that we could conclude to some factors of prognosis concerning the management of these tumors. RESULTS: The mean age of our patients is 33.84 years. We had 57 males and 63 females. The most frequent revealing symptom was motor trouble presented as frequent as 77.5% of the patients. Glial tumors were represented in 81 of the cases (67.5%) and nonglial by 39 cases (32.5%). Glial tumors we found were essentially 39 ependymomas and 35 astrocytomas. Surgical resection is key in the management of these lesions; the quality of tumoral resection was a significant factor of disease progression as subtotal resection is correlated to more important progression than total one. CONCLUSION: We conclude this work with some statements. In terms of functional results, age is not a significant factor. Presurgical functional state, the histological type, and the extent of surgical resection are the important factors. Wolters Kluwer - Medknow 2021 2021-09-08 /pmc/articles/PMC8501820/ /pubmed/34728994 http://dx.doi.org/10.4103/jcvjs.jcvjs_64_21 Text en Copyright: © 2021 Journal of Craniovertebral Junction and Spine https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Hachicha, Anis
Belhaj, Ala
Karmeni, Nadhir
Slimane, Abdelhafidh
Bouali, Sofiene
Kallel, Jalel
Intramedullary spinal cord tumors: A retrospective multicentric study
title Intramedullary spinal cord tumors: A retrospective multicentric study
title_full Intramedullary spinal cord tumors: A retrospective multicentric study
title_fullStr Intramedullary spinal cord tumors: A retrospective multicentric study
title_full_unstemmed Intramedullary spinal cord tumors: A retrospective multicentric study
title_short Intramedullary spinal cord tumors: A retrospective multicentric study
title_sort intramedullary spinal cord tumors: a retrospective multicentric study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501820/
https://www.ncbi.nlm.nih.gov/pubmed/34728994
http://dx.doi.org/10.4103/jcvjs.jcvjs_64_21
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