Cargando…

Alternative 3′ UTRs play a widespread role in translation-independent mRNA association with the endoplasmic reticulum

Transcripts encoding membrane and secreted proteins are known to associate with the endoplasmic reticulum (ER) through translation. Here, using cell fractionation, polysome profiling, and 3′ end sequencing, we show that transcripts differ substantially in translation-independent ER association (TiER...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cheng, Larry C., Zheng, Dinghai, Zhang, Qiang, Guvenek, Aysegul, Cheng, Hong, Tian, Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501909/ https://www.ncbi.nlm.nih.gov/pubmed/34289366 http://dx.doi.org/10.1016/j.celrep.2021.109407

Ejemplares similares

Neuronal Cells Display Distinct Stability Controls of Alternative Polyadenylation mRNA Isoforms, Long Non-Coding RNAs, and Mitochondrial RNAs
por: Guvenek, Aysegul, et al.
Publicado: (2022)

Translation- and SRP-independent mRNA targeting to the endoplasmic reticulum in the yeast Saccharomyces cerevisiae
por: Kraut-Cohen, Judith, et al.
Publicado: (2013)

Widespread transcript shortening through alternative polyadenylation in secretory cell differentiation
por: Cheng, Larry C., et al.
Publicado: (2020)

Cellular stress alters 3′UTR landscape through alternative polyadenylation and isoform-specific degradation
por: Zheng, Dinghai, et al.
Publicado: (2018)

A widespread alternate form of cap-dependent mRNA translation initiation
por: de la Parra, Columba, et al.
Publicado: (2018)

Endoplasmic reticulum—shape and function in stress translation
por: Brandizzi, Federica, et al.
Publicado: (2014)

mRNA Localization to the Endoplasmic Reticulum in Plant Endosperm Cells
por: Zhang, Laining, et al.
Publicado: (2022)

p180 Promotes the Ribosome-Independent Localization of a Subset of mRNA to the Endoplasmic Reticulum
por: Cui, Xianying A., et al.
Publicado: (2012)

Activity-Dependent Regulation of Alternative Cleavage and Polyadenylation During Hippocampal Long-Term Potentiation
por: Fontes, Mariana M., et al.
Publicado: (2017)

Cap-independent translation through the p27 5′-UTR
por: Jiang, Hong, et al.
Publicado: (2007)

CRISPRpas: programmable regulation of alternative polyadenylation by dCas9
por: Shin, Jihae, et al.
Publicado: (2021)

Translational Regulations in Response to Endoplasmic Reticulum Stress in Cancers
por: Jaud, Manon, et al.
Publicado: (2020)

Widespread and extensive lengthening of 3′ UTRs in the mammalian brain
por: Miura, Pedro, et al.
Publicado: (2013)

An alternative pathway for membrane protein biogenesis at the endoplasmic reticulum
por: O’Keefe, Sarah, et al.
Publicado: (2021)

3′READS + RIP defines differential Staufen1 binding to alternative 3′UTR isoforms and reveals structures and sequence motifs influencing binding and polysome association
por: Zheng, Dinghai, et al.
Publicado: (2020)

p53-mediated control of gene expression via mRNA translation during Endoplasmic Reticulum stress
por: López, Ignacio, et al.
Publicado: (2015)

Regulation of Sumo mRNA during Endoplasmic Reticulum Stress
por: Moore, Kristin A., et al.
Publicado: (2013)

Acute Endoplasmic Reticulum Stress-Independent Unconventional Splicing of XBP1 mRNA in the Nucleus of Mammalian Cells
por: Wang, Yuanyuan, et al.
Publicado: (2015)

CReP mediates selective translation initiation at the endoplasmic reticulum
por: Kastan, Jonathan P., et al.
Publicado: (2020)

Regulation of Translation, Translocation, and Degradation of Proteins at the Membrane of the Endoplasmic Reticulum
por: Daverkausen-Fischer, Lea, et al.
Publicado: (2022)

Hierarchical regulation of mRNA partitioning between the cytoplasm and the endoplasmic reticulum of mammalian cells
por: Chen, Qiang, et al.
Publicado: (2011)

THE ENDOPLASMIC RETICULUM
por: Palade, George E.
Publicado: (1956)

Alternative splicing of its 5′-UTR limits CD20 mRNA translation and enables resistance to CD20-directed immunotherapies
por: Ang, Zhiwei, et al.
Publicado: (2023)

Lost in Translation: Endoplasmic Reticulum–Mitochondria Crosstalk in Idiopathic Pulmonary Fibrosis
por: Bueno, Marta, et al.
Publicado: (2020)

Local translation of yeast ERG4 mRNA at the endoplasmic reticulum requires the brefeldin A resistance protein Bfr1
por: Manchalu, Srinivas, et al.
Publicado: (2019)

Translational derepression of Elavl4 isoforms at their alternative 5′ UTRs determines neuronal development
por: Popovitchenko, Tatiana, et al.
Publicado: (2020)

Golgi clusters and vesicles mediate mitotic inheritance independently of the endoplasmic reticulum
por: Jokitalo, Eija, et al.
Publicado: (2001)

Mitofusin-2 Independent Juxtaposition of Endoplasmic Reticulum and Mitochondria: An Ultrastructural Study
por: Cosson, Pierre, et al.
Publicado: (2012)

Protein N-Myristoylation Plays a Critical Role in the Endoplasmic Reticulum Morphological Change Induced by Overexpression of Protein Lunapark, an Integral Membrane Protein of the Endoplasmic Reticulum
por: Moriya, Koko, et al.
Publicado: (2013)

Endoplasmic Reticulum Stress Plays a Key Role in the Pathogenesis of Diabetic Peripheral Neuropathy
por: Lupachyk, Sergey, et al.
Publicado: (2013)

Dissociation of ERMES clusters plays a key role in attenuating the endoplasmic reticulum stress
por: Kakimoto-Takeda, Yuriko, et al.
Publicado: (2022)

Hydrogen sulfide plays an important role by regulating endoplasmic reticulum stress in myocardial diseases
por: Zhao, Huijie, et al.
Publicado: (2023)

Binding of viral glycoprotein mRNA to endoplasmic reticulum membranes is disrupted by puromycin
Publicado: (1977)

Construction of the endoplasmic reticulum
Publicado: (1989)

A combinatorial code for mRNA 3′-UTR-mediated translational control in the mouse oocyte
por: Dai, Xing-Xing, et al.
Publicado: (2019)

Global 5′-UTR RNA structure regulates translation of a SERPINA1 mRNA
por: Grayeski, Philip J, et al.
Publicado: (2022)

JUN mRNA Translation Regulation is Mediated by Multiple 5’ UTR and Start Codon Features
por: González-Sánchez, Angélica M., et al.
Publicado: (2023)

The Perlman syndrome DIS3L2 exoribonuclease safeguards endoplasmic reticulum-targeted mRNA translation and calcium ion homeostasis
por: Pirouz, Mehdi, et al.
Publicado: (2020)

Exploring mRNA 3′-UTR G-quadruplexes: evidence of roles in both alternative polyadenylation and mRNA shortening
por: Beaudoin, Jean-Denis, et al.
Publicado: (2013)

Alternative glycosylation controls endoplasmic reticulum dynamics and tubular extension in mammalian cells
por: Kerselidou, Despoina, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_a73kkg6psuni627ijrj4gbql1u