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ZFC3H1 prevents RNA trafficking into nuclear speckles through condensation

Controlling proper RNA pool for nuclear export is important for accurate gene expression. ZFC3H1 is a key controller that not only facilitates nuclear exosomal degradation, but also retains its bound polyadenylated RNAs in the nucleus upon exosome inactivation. However, how ZFC3H1 retains RNAs and h...

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Detalles Bibliográficos
Autores principales: Wang, Yimin, Fan, Jing, Wang, Jianshu, Zhu, Yi, Xu, Lin, Tong, Deng, Cheng, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501945/
https://www.ncbi.nlm.nih.gov/pubmed/34530450
http://dx.doi.org/10.1093/nar/gkab774