The CRL4(DTL) E3 ligase induces degradation of the DNA replication initiation factor TICRR/TRESLIN specifically during S phase

A DNA replication program, which ensures that the genome is accurately and wholly replicated, is established during G1, before the onset of S phase. In G1, replication origins are licensed, and upon S phase entry, a subset of these will form active replisomes. Tight regulation of the number of activ...

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Detalles Bibliográficos
Autores principales: Wittig, Kimberlie A, Sansam, Courtney G, Noble, Tyler D, Goins, Duane, Sansam, Christopher L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501952/
https://www.ncbi.nlm.nih.gov/pubmed/34534348
http://dx.doi.org/10.1093/nar/gkab805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501952/
https://www.ncbi.nlm.nih.gov/pubmed/34534348
http://dx.doi.org/10.1093/nar/gkab805

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