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The CRL4(DTL) E3 ligase induces degradation of the DNA replication initiation factor TICRR/TRESLIN specifically during S phase
A DNA replication program, which ensures that the genome is accurately and wholly replicated, is established during G1, before the onset of S phase. In G1, replication origins are licensed, and upon S phase entry, a subset of these will form active replisomes. Tight regulation of the number of activ...
Autores principales: | Wittig, Kimberlie A, Sansam, Courtney G, Noble, Tyler D, Goins, Duane, Sansam, Christopher L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501952/ https://www.ncbi.nlm.nih.gov/pubmed/34534348 http://dx.doi.org/10.1093/nar/gkab805 |
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