Structural basis for activation of Swi2/Snf2 ATPase RapA by RNA polymerase

RapA is a bacterial RNA polymerase (RNAP)-associated Swi2/Snf2 ATPase that stimulates RNAP recycling. The ATPase activity of RapA is autoinhibited by its N-terminal domain (NTD) but activated with RNAP bound. Here, we report a 3.4-Å cryo-EM structure of Escherichia coli RapA–RNAP elongation complex,...

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Detalles Bibliográficos
Autores principales: Shi, Wei, Zhou, Wei, Chen, Ming, Yang, Yang, Hu, Yangbo, Liu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501970/
https://www.ncbi.nlm.nih.gov/pubmed/34428297
http://dx.doi.org/10.1093/nar/gkab744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501970/
https://www.ncbi.nlm.nih.gov/pubmed/34428297
http://dx.doi.org/10.1093/nar/gkab744

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