The β3/5 Integrin-MMP9 Axis Regulates Pulmonary Inflammatory Response and Endothelial Leakage in Acute Lung Injury

BACKGROUND: Acute lung injury (ALI) is a severe respiratory disease with high rates of morbidity and mortality. Many mediators regarding endogenous or exogenous are involved in the pathophysiology of ALI. Here, we have uncovered the involvement of integrins and matrix metalloproteinases, as critical...

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Detalles Bibliográficos
Autores principales: Tong, Yao, Bao, Chengrong, Xu, Yi-Qiong, Tao, Lei, Zhou, Yao, Zhuang, Lei, Meng, Ying, Zhang, Hui, Xue, Jingjing, Wang, Weijun, Zhang, Lele, Pan, Qingbo, Shao, Zhenzhen, Hu, Tianran, Guo, Qian, Xue, Qingsheng, Lu, Han, Luo, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502060/
https://www.ncbi.nlm.nih.gov/pubmed/34675589
http://dx.doi.org/10.2147/JIR.S331939

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