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Progressive Pontine-Medullary Dysfunction Leads to REM Sleep Behavior Disorder Symptoms in a Chronic Model of Parkinson’s Disease

BACKGROUND: Clinical observations reveal that rapid eye movement (REM) sleep behavior disorder (RBD) often develops prior to alpha-synucleinopathies including Parkinson’s disease (PD). However, a causal relationship between alpha-synucleinopathy and Parkinsonian neurodegeneration has not been deline...

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Detalles Bibliográficos
Autores principales: Du, Lida, Xu, Linhao, Liang, Tuo, Wing, Yun-Kwok, Ke, Ya, Yung, Wing-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502064/
https://www.ncbi.nlm.nih.gov/pubmed/34675721
http://dx.doi.org/10.2147/NSS.S328365