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Synergism of rMV-Hu191 with cisplatin to treat gastric cancer by acid sphingomyelinase-mediated apoptosis requiring integrity of lipid raft microdomains

BACKGROUND: DDP-based chemotherapy is one of the first-line treatment in GC. However, the therapeutic efficacy of DDP is limited due to side effects. Therefore, it is of great significance to develop novel adjuvants to synergize with DDP. We had demonstrated previously that rMV-Hu191 had antitumor a...

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Detalles Bibliográficos
Autores principales: Lv, Yao, Zhang, Chu-di, Wang, Yi-long, Zhou, Dong-ming, Zhu, Meng-ying, Hao, Xiao-qiang, Wang, Jin-hu, Gu, Wei-zhong, Shen, Hong-qiang, Lou, Jin-gan, Wu, Ben-qing, Chen, Pei-chun, Zhao, Zheng-yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502160/
https://www.ncbi.nlm.nih.gov/pubmed/34251544
http://dx.doi.org/10.1007/s10120-021-01210-8