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Synergism of rMV-Hu191 with cisplatin to treat gastric cancer by acid sphingomyelinase-mediated apoptosis requiring integrity of lipid raft microdomains
BACKGROUND: DDP-based chemotherapy is one of the first-line treatment in GC. However, the therapeutic efficacy of DDP is limited due to side effects. Therefore, it is of great significance to develop novel adjuvants to synergize with DDP. We had demonstrated previously that rMV-Hu191 had antitumor a...
Autores principales: | Lv, Yao, Zhang, Chu-di, Wang, Yi-long, Zhou, Dong-ming, Zhu, Meng-ying, Hao, Xiao-qiang, Wang, Jin-hu, Gu, Wei-zhong, Shen, Hong-qiang, Lou, Jin-gan, Wu, Ben-qing, Chen, Pei-chun, Zhao, Zheng-yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502160/ https://www.ncbi.nlm.nih.gov/pubmed/34251544 http://dx.doi.org/10.1007/s10120-021-01210-8 |
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