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Glioblastoma cells express crucial enzymes involved in androgen synthesis: 3β‐hydroxysteroid dehydrogenase, 17‐20α‐hydroxylase, 17β‐hydroxysteroid dehydrogenase and 5α‐reductase

Glioblastoma (GB) is the most common and aggressive primary brain tumour in adult humans. Therapeutic resistance and tumour recurrence after surgical removal contribute to poor prognosis for glioblastoma patients. Men are known to be more likely than women to develop an aggressive form of GB, and di...

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Detalles Bibliográficos
Autores principales: Mondragón, Jose Antonio, Serrano, Yesenia, Torres, Andrea, Orozco, Martin, Segovia, Jose, Manjarrez, Gabriel, Romano, Marta Catalina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502219/
https://www.ncbi.nlm.nih.gov/pubmed/34505421
http://dx.doi.org/10.1002/edm2.289