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Integrated medical resource consumption stratification in hospitalized patients: an Auto Triage Management model based on accurate risk, cost and length of stay prediction

Triage management plays important roles in hospitalized patients for disease severity stratification and medical burden analysis. Although progression risks have been extensively researched for numbers of diseases, other crucial indicators that reflect patients’ economic and time costs have not been...

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Autores principales: Zhong, Qin, Li, Zongren, Wang, Wenjun, Zhang, Lei, He, Kunlun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science China Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502627/
https://www.ncbi.nlm.nih.gov/pubmed/34632536
http://dx.doi.org/10.1007/s11427-021-1987-5
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author Zhong, Qin
Li, Zongren
Wang, Wenjun
Zhang, Lei
He, Kunlun
author_facet Zhong, Qin
Li, Zongren
Wang, Wenjun
Zhang, Lei
He, Kunlun
author_sort Zhong, Qin
collection PubMed
description Triage management plays important roles in hospitalized patients for disease severity stratification and medical burden analysis. Although progression risks have been extensively researched for numbers of diseases, other crucial indicators that reflect patients’ economic and time costs have not been systematically studied. To address the problems, we developed an automatic deep learning based Auto Triage Management (ATM) Framework capable of accurately modelling patients’ disease progression risk and health economic evaluation. Based on them, we can first discover the relationship between disease progression and medical system cost, find potential features that can more precisely aid patient triage in resource allocation, and allow treatment plan searching that has cured patients. Applying ATM in COVID-19, we built a joint model to predict patients’ risk, the total length of stay (LoS) and cost when at-admission, and remaining LoS and cost at a given hospitalized time point, with C-index 0.930 and 0.869 for risk prediction, mean absolute error (MAE) of 5.61 and 5.90 days for total LoS prediction in internal and external validation data. SUPPORTING INFORMATION: The supporting information is available online at 10.1007/s11427-021-1987-5. The supporting materials are published as submitted, without typesetting or editing. The responsibility for scientific accuracy and content remains entirely with the authors.
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spelling pubmed-85026272021-10-12 Integrated medical resource consumption stratification in hospitalized patients: an Auto Triage Management model based on accurate risk, cost and length of stay prediction Zhong, Qin Li, Zongren Wang, Wenjun Zhang, Lei He, Kunlun Sci China Life Sci Research Paper Triage management plays important roles in hospitalized patients for disease severity stratification and medical burden analysis. Although progression risks have been extensively researched for numbers of diseases, other crucial indicators that reflect patients’ economic and time costs have not been systematically studied. To address the problems, we developed an automatic deep learning based Auto Triage Management (ATM) Framework capable of accurately modelling patients’ disease progression risk and health economic evaluation. Based on them, we can first discover the relationship between disease progression and medical system cost, find potential features that can more precisely aid patient triage in resource allocation, and allow treatment plan searching that has cured patients. Applying ATM in COVID-19, we built a joint model to predict patients’ risk, the total length of stay (LoS) and cost when at-admission, and remaining LoS and cost at a given hospitalized time point, with C-index 0.930 and 0.869 for risk prediction, mean absolute error (MAE) of 5.61 and 5.90 days for total LoS prediction in internal and external validation data. SUPPORTING INFORMATION: The supporting information is available online at 10.1007/s11427-021-1987-5. The supporting materials are published as submitted, without typesetting or editing. The responsibility for scientific accuracy and content remains entirely with the authors. Science China Press 2021-10-08 2022 /pmc/articles/PMC8502627/ /pubmed/34632536 http://dx.doi.org/10.1007/s11427-021-1987-5 Text en © Science China Press and Springer-Verlag GmbH Germany, part of Springer Nature 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Research Paper
Zhong, Qin
Li, Zongren
Wang, Wenjun
Zhang, Lei
He, Kunlun
Integrated medical resource consumption stratification in hospitalized patients: an Auto Triage Management model based on accurate risk, cost and length of stay prediction
title Integrated medical resource consumption stratification in hospitalized patients: an Auto Triage Management model based on accurate risk, cost and length of stay prediction
title_full Integrated medical resource consumption stratification in hospitalized patients: an Auto Triage Management model based on accurate risk, cost and length of stay prediction
title_fullStr Integrated medical resource consumption stratification in hospitalized patients: an Auto Triage Management model based on accurate risk, cost and length of stay prediction
title_full_unstemmed Integrated medical resource consumption stratification in hospitalized patients: an Auto Triage Management model based on accurate risk, cost and length of stay prediction
title_short Integrated medical resource consumption stratification in hospitalized patients: an Auto Triage Management model based on accurate risk, cost and length of stay prediction
title_sort integrated medical resource consumption stratification in hospitalized patients: an auto triage management model based on accurate risk, cost and length of stay prediction
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502627/
https://www.ncbi.nlm.nih.gov/pubmed/34632536
http://dx.doi.org/10.1007/s11427-021-1987-5
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