Pathogenesis and drug response of iPSC-derived cardiomyocytes from two Brugada syndrome patients with different Na(v)1.5-subunit mutations

Brugada syndrome (BrS) is a complex genetic cardiac ion channel disease that causes a high predisposition to sudden cardiac death. Considering that its heterogeneity in clinical manifestations may result from genetic background, the application of patient-specific induced pluripotent stem cell-deriv...

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Detalles Bibliográficos
Autores principales: Zhu, Yue, Wang, Linlin, Cui, Chang, Qin, Huiyuan, Chen, Hongwu, Chen, Shaojie, Lin, Yongping, Cheng, Hongyi, Jiang, Xiaohong, Chen, Minglong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502687/
https://www.ncbi.nlm.nih.gov/pubmed/34628405
http://dx.doi.org/10.7555/JBR.35.20210045

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