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Regulatory role of sorting nexin 5 in protein stability and vesicular targeting of vesicular acetylcholine transporter to synaptic vesicle-like vesicles in PC12 cells

Accurate targeting of vesicular acetylcholine transporter (VAChT) to synaptic vesicles (SVs) is indispensable for efficient cholinergic transmission. Previous studies have suggested that the dileucine motif within the C-terminus of the transporter is sufficient for its targeting to SVs. However, the...

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Detalles Bibliográficos
Autores principales: Sun, Meihen, Han, Xu, Chang, Fei, Xu, Hongfei, Colgan, Lesley, Liu, Yongjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502691/
https://www.ncbi.nlm.nih.gov/pubmed/34230437
http://dx.doi.org/10.7555/JBR.34.20200095