Intraocular therapy in noninfectious uveitis

Systemic corticosteroids and immunosuppressant agents are the mainstay of therapy for non-infectious uveitis (NIU). However, the risks associated with systemic administration and the need of delivering an effective and safe anti-inflammatory treatment targeted to the site of inflammation have prompt...

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Autores principales: Modugno, Rocco Luigi, Testi, Ilaria, Pavesio, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502718/
https://www.ncbi.nlm.nih.gov/pubmed/34632541
http://dx.doi.org/10.1186/s12348-021-00267-x
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author Modugno, Rocco Luigi
Testi, Ilaria
Pavesio, Carlos
author_facet Modugno, Rocco Luigi
Testi, Ilaria
Pavesio, Carlos
author_sort Modugno, Rocco Luigi
collection PubMed
description Systemic corticosteroids and immunosuppressant agents are the mainstay of therapy for non-infectious uveitis (NIU). However, the risks associated with systemic administration and the need of delivering an effective and safe anti-inflammatory treatment targeted to the site of inflammation have prompt the use of local therapy in the management of NIU. This review will analyse the different local treatment options available, including corticosteroids, anti-vascular endothelial growth factor (VEGF), methotrexate and the recent biologics.
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spelling pubmed-85027182021-10-22 Intraocular therapy in noninfectious uveitis Modugno, Rocco Luigi Testi, Ilaria Pavesio, Carlos J Ophthalmic Inflamm Infect Review Systemic corticosteroids and immunosuppressant agents are the mainstay of therapy for non-infectious uveitis (NIU). However, the risks associated with systemic administration and the need of delivering an effective and safe anti-inflammatory treatment targeted to the site of inflammation have prompt the use of local therapy in the management of NIU. This review will analyse the different local treatment options available, including corticosteroids, anti-vascular endothelial growth factor (VEGF), methotrexate and the recent biologics. Springer Berlin Heidelberg 2021-10-10 /pmc/articles/PMC8502718/ /pubmed/34632541 http://dx.doi.org/10.1186/s12348-021-00267-x Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review
Modugno, Rocco Luigi
Testi, Ilaria
Pavesio, Carlos
Intraocular therapy in noninfectious uveitis
title Intraocular therapy in noninfectious uveitis
title_full Intraocular therapy in noninfectious uveitis
title_fullStr Intraocular therapy in noninfectious uveitis
title_full_unstemmed Intraocular therapy in noninfectious uveitis
title_short Intraocular therapy in noninfectious uveitis
title_sort intraocular therapy in noninfectious uveitis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502718/
https://www.ncbi.nlm.nih.gov/pubmed/34632541
http://dx.doi.org/10.1186/s12348-021-00267-x
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