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Tumor-immune ecosystem dynamics define an individual Radiation Immune Score to predict pan-cancer radiocurability()

Radiotherapy efficacy is the result of radiation-mediated cytotoxicity coupled with stimulation of antitumor immune responses. We develop an in silico 3-dimensional agent-based model of diverse tumor-immune ecosystems (TIES) represented as anti- or pro-tumor immune phenotypes. We validate the model...

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Detalles Bibliográficos
Autores principales:	Alfonso, Juan C.L., Grass, G. Daniel, Welsh, Eric, Ahmed, Kamran A., Teer, Jamie K., Pilon-Thomas, Shari, Harrison, Louis B., Cleveland, John L., Mulé, James J., Eschrich, Steven A., Torres-Roca, Javier F., Enderling, Heiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502777/ https://www.ncbi.nlm.nih.gov/pubmed/34619428 http://dx.doi.org/10.1016/j.neo.2021.09.003

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