Cargando…

Fascin-1 is Highly Expressed Specifically in Microglia After Spinal Cord Injury and Regulates Microglial Migration

Recent research indicates that after spinal cord injury (SCI), microglia accumulate at the borders of lesions between astrocytic and fibrotic scars and perform inflammation-limiting and neuroprotective functions, however, the mechanism of microglial migration remains unclear. Fascin-1 is a key actin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Shuisheng, Cheng, Li, Tian, Dasheng, Li, Ziyu, Yao, Fei, Luo, Yang, Liu, Yanchang, Zhu, Zhenyu, Zheng, Meige, Jing, Juehua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502808/ https://www.ncbi.nlm.nih.gov/pubmed/34646136 http://dx.doi.org/10.3389/fphar.2021.729524

Ejemplares similares

M2 Macrophages Promote PDGFRβ(+) Pericytes Migration After Spinal Cord Injury in Mice via PDGFB/PDGFRβ Pathway
por: Li, Ziyu, et al.
Publicado: (2021)

Tocilizumab promotes repair of spinal cord injury by facilitating the restoration of tight junctions between vascular endothelial cells
por: Luo, Yang, et al.
Publicado: (2023)

Fibrotic Scar After Spinal Cord Injury: Crosstalk With Other Cells, Cellular Origin, Function, and Mechanism
por: Li, Ziyu, et al.
Publicado: (2021)

SU16f inhibits fibrotic scar formation and facilitates axon regeneration and locomotor function recovery after spinal cord injury by blocking the PDGFRβ pathway
por: Li, Ziyu, et al.
Publicado: (2022)

TAZ Induces Migration of Microglia and Promotes Neurological Recovery After Spinal Cord Injury
por: Hu, Xuyang, et al.
Publicado: (2022)

Corrigendum: TAZ induces migration of microglia and promotes neurological recovery after spinal cord injury
por: Hu, Xuyang, et al.
Publicado: (2022)

D-4F, an apolipoprotein A-I mimetic, promotes the clearance of myelin debris and the reduction of foamy macrophages after spinal cord injury
por: Li, Jinxin, et al.
Publicado: (2022)

Differences of Microglia in the Brain and the Spinal Cord
por: Xuan, Fang-Ling, et al.
Publicado: (2019)

Nimodipine Promotes Functional Recovery After Spinal Cord Injury in Rats
por: Guo, Fangliang, et al.
Publicado: (2021)

CO-Releasing Molecule (CORM)-3 Ameliorates Spinal Cord-Blood Barrier Disruption Following Injury to the Spinal Cord
por: Zheng, Gang, et al.
Publicado: (2020)

Ester Hydrolysis Differentially Reduces Aconitine-Induced Anti-hypersensitivity and Acute Neurotoxicity: Involvement of Spinal Microglial Dynorphin Expression and Implications for Aconitum Processing
por: Li, Teng-Fei, et al.
Publicado: (2016)

Gankyrin activates the hedgehog signalling to drive metastasis in osteosarcoma
por: Wang, Chongchong, et al.
Publicado: (2021)

Clinical efficacy of percutaneous transforaminal endoscopic discectomy in treating adolescent lumbar disc herniation
por: Liu, Wei, et al.
Publicado: (2019)

The Effect of Plasma Rich in Growth Factors on Microglial Migration, Macroglial Gliosis and Proliferation, and Neuronal Survival
por: Ruzafa, Noelia, et al.
Publicado: (2021)

Experimental treatments to attenuate blood spinal cord barrier rupture in rats with traumatic spinal cord injury: A meta-analysis and systematic review
por: Deng, Li, et al.
Publicado: (2022)

Microglia in the spinal cord and neuropathic pain
por: Tsuda, Makoto
Publicado: (2015)

Spinal Cord Microglia in Health and Disease
por: Kolos, E. A., et al.
Publicado: (2020)

Continual Deletion of Spinal Microglia Reforms Astrocyte Scar Favoring Axonal Regeneration
por: Xia, Longkuo, et al.
Publicado: (2022)

The Role of Biomaterials as Angiogenic Modulators of Spinal Cord Injury: Mimetics of the Spinal Cord, Cell and Angiogenic Factor Delivery Agents
por: Rocha, Luís A., et al.
Publicado: (2018)

The Anti-neuroinflammatory Activity of Tectorigenin Pretreatment via Downregulated NF-κB and ERK/JNK Pathways in BV-2 Microglial and Microglia Inactivation in Mice With Lipopolysaccharide
por: Lim, Hye-Sun, et al.
Publicado: (2018)

Melatonin Synergizes With Methylprednisolone to Ameliorate Acute Spinal Cord Injury
por: Bi, Jiaqi, et al.
Publicado: (2022)

Fascin Regulates Nuclear Movement and Deformation in Migrating Cells
por: Jayo, Asier, et al.
Publicado: (2016)

The Rho-associated kinase inhibitors Y27632 and fasudil promote microglial migration in the spinal cord via the ERK signaling pathway
por: Fu, Pei-Cai, et al.
Publicado: (2018)

Paclitaxel-incorporated nanoparticles improve functional recovery after spinal cord injury
por: Zhang, Xinzhu, et al.
Publicado: (2022)

Emerging Roles of Microglia Depletion in the Treatment of Spinal Cord Injury
por: Deng, Junhao, et al.
Publicado: (2022)

Biomaterials for Local, Controlled Drug Delivery to the Injured Spinal Cord
por: Ziemba, Alexis M., et al.
Publicado: (2017)

Recombinant Adenoviruses for Delivery of Therapeutics Following Spinal Cord Injury
por: Sosnovtseva, Anastasiia O., et al.
Publicado: (2022)

Protective effect of zinc oxide nanoparticles on spinal cord injury
por: Liu, Jia, et al.
Publicado: (2022)

Catalpol ameliorates CFA-induced inflammatory pain by targeting spinal cord and peripheral inflammation
por: Zhao, Baoxia, et al.
Publicado: (2022)

Baicalein Attenuates Pyroptosis and Endoplasmic Reticulum Stress Following Spinal Cord Ischemia-Reperfusion Injury via Autophagy Enhancement
por: Wu, Chenyu, et al.
Publicado: (2020)

Application of natural antioxidants from traditional Chinese medicine in the treatment of spinal cord injury
por: Huang, Zhihua, et al.
Publicado: (2022)

Translocator Protein 18 kDa (TSPO) Deficiency Inhibits Microglial Activation and Impairs Mitochondrial Function
por: Yao, Rumeng, et al.
Publicado: (2020)

Fascin in Cell Migration: More Than an Actin Bundling Protein
por: Lamb, Maureen C., et al.
Publicado: (2020)

Andrographolide contributes to spinal cord injury repair via inhibition of apoptosis, oxidative stress and inflammation
por: Li, Zhen, et al.
Publicado: (2022)

Microglia and Spinal Cord Synaptic Plasticity in Persistent Pain
por: Taves, Sarah, et al.
Publicado: (2013)

Current Knowledge of Microglia in Traumatic Spinal Cord Injury
por: Xu, Lintao, et al.
Publicado: (2022)

Scorpion Venom Heat-Resistant Peptide Attenuates Microglia Activation and Neuroinflammation
por: Wu, Xue-Fei, et al.
Publicado: (2021)

MMP24 Contributes to Neuropathic Pain in an FTO-Dependent Manner in the Spinal Cord Neurons
por: Ma, Longfei, et al.
Publicado: (2021)

M1-type microglia can induce astrocytes to deposit chondroitin sulfate proteoglycan after spinal cord injury
por: Yu, Shui-Sheng, et al.
Publicado: (2021)

Neonatal microglia-organized scar-free spinal cord repair
por: Li, Yi, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_if1gr1tmdksciu0hscrtin42g7