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Mast Cells Are Identified in the Lung Parenchyma of Wild Mice, Which Can Be Recapitulated in Naturalized Laboratory Mice

BACKGROUND: It is well documented that laboratory mice bred and maintained in ultra-hygienic specific pathogen-free (SPF) barriers display reduced richness and complexity of microbiota compared with wild mice. The laboratory mice profoundly lack lung parenchymal mast cells. Hence, we aimed to invest...

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Detalles Bibliográficos
Autores principales: Yeh, Yu-Wen, Chaudhuri, Arka Sen, Zhou, Ling, Fang, Yu, Boysen, Preben, Xiang, Zou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502827/
https://www.ncbi.nlm.nih.gov/pubmed/34646271
http://dx.doi.org/10.3389/fimmu.2021.736692