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The Cellular Origins of Cancer-Associated Fibroblasts and Their Opposing Contributions to Pancreatic Cancer Growth

Pancreatic tumors are known to harbor an abundant and highly desmoplastic stroma. Among the various cell types that reside within tumor stroma, cancer-associated fibroblasts (CAFs) have gained a lot of attention in the cancer field due to their contributions to carcinogenesis and tumor architecture....

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Detalles Bibliográficos
Autores principales: Manoukian, Paul, Bijlsma, Maarten, van Laarhoven, Hanneke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502878/
https://www.ncbi.nlm.nih.gov/pubmed/34646829
http://dx.doi.org/10.3389/fcell.2021.743907