Unsupervised Clustering Reveals Distinct Subtypes of Biliary Atresia Based on Immune Cell Types and Gene Expression

BACKGROUND: Biliary atresia (BA) is a severe cholangiopathy of early infancy that destroys cholangiocytes, obstructs ductular pathways and if left untreated, culminates to liver cirrhosis. Mechanisms underlying the etiological heterogeneity remain elusive and few studies have attempted phenotyping B...

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Detalles Bibliográficos
Autores principales: Pang, Xiuqing, Cao, Jing, Chen, Shuru, Gao, Zhiliang, Liu, Guangjian, Chong, Yutian, Chen, Zhuanggui, Gong, Jiao, Li, Xinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502897/
https://www.ncbi.nlm.nih.gov/pubmed/34646264
http://dx.doi.org/10.3389/fimmu.2021.720841

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