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Emerging Advances in Combinatorial Treatments of Epigenetically Altered Pediatric High-Grade H3K27M Gliomas

Somatic mutations in histone encoding genes result in gross alterations in the epigenetic landscape. Diffuse intrinsic pontine glioma (DIPG) is a pediatric high-grade glioma (pHGG) and one of the most challenging cancers to treat, with only 1% surviving for 5 years. Due to the location in the brains...

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Detalles Bibliográficos
Autores principales:	Leszczynska, Katarzyna B., Jayaprakash, Chinchu, Kaminska, Bozena, Mieczkowski, Jakub
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8503186/ https://www.ncbi.nlm.nih.gov/pubmed/34646308 http://dx.doi.org/10.3389/fgene.2021.742561

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